Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 5/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3217919 | 0.89 | ALDH1A1 (0.50) | CA2CA12CA9ALOX15ALDH1A1 | |
| SCHEMBL3208060 | 0.80 | CA2 (0.38) | CA2CA12CA9ALDH1A1GAA | |
| SCHEMBL3208052 | 0.79 | CA2 (0.38) | CA2CA12CA9CA1CA14 | |
| SCHEMBL5127346 | 0.79 | CA2 (0.64) | CA2CA12CA9ALOX15ALDH1A1 | |
| SCHEMBL3221256 | 0.77 | CA2 (0.60) | CA2CA12CA9CA1CA14 | |
| SCHEMBL3215472 | 0.76 | CYP2C19 (0.36) | CA2CA12ALDH1A1KMT2AGAA | |
| SCHEMBL7081057 | 0.76 | CA2 (0.63) | CA2CA12CA9CA1CA14 | |
| SCHEMBL7085537 | 0.76 | CA2 (0.63) | CA2CA12CA9CA1CA14 | |
| SCHEMBL3219367 | 0.74 | ALDH1A1 (0.39) | CA2CA12CA9ALDH1A1CA1 | |
| SCHEMBL3204486 | 0.74 | MAPK1 (0.47) | CA2CA12CA9ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041892-A1 | Therapeutic agent for diabetes | ABE HIDENORI | 2010-02-18 | — | — | US | disclosed |
| US-20090270631-A1 | Therapeutic agent for diabetes | ABE HIDENORI | 2009-10-29 | — | — | US | disclosed |
| US-20080009530-A1 | Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270631-A1 | Therapeutic agent for diabetes | FABP4, SLC5A1, SLC5A2 | CA2 1474/4885CA12 3251/4885CA9 2144/4885 |
| US-20080009530-A1 | Therapeutic Agent for Diabetes | FABP4, SLC5A1, SLC5A2 | CA2 1306/4885CA12 3135/4885CA9 2659/4885 |
| US-20100041892-A1 | Therapeutic agent for diabetes | FABP4, SLC5A1, SLC5A2 | CA2 1474/4885CA12 3251/4885CA9 2144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.