SCHEMBL3208187

SCHEMBL3208187

CC(C)c1cccc(C(C)C)c1NN=C(CC1=C(C(C)(C)C)C=CC1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.38
LMNA P02545 1/20 0.38
MEN1 O00255 4/20 0.32
TDP1 Q9NUW8 3/20 0.32
ALDH1A1 P00352 3/20 0.31
MAPT P10636 3/20 0.31
GAA P10253 2/20 0.31
SOAT2 O75908 1/20 0.31
SOAT1 P35610 1/20 0.31
HTT P42858 1/20 0.31
MAPK1 P28482 1/20 0.31
KDM4E B2RXH2 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
GABRA1 P14867 1/20 0.30
GABRG2 P18507 1/20 0.30
GABRB3 P28472 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3214886 0.85 KMT2A (0.40) KMT2ALMNAMEN1TDP1ALDH1A1
SCHEMBL3214903 0.85 ALDH1A1 (0.43) KMT2ALMNAMEN1TDP1ALDH1A1
SCHEMBL3199281 0.83 KMT2A (0.34) KMT2ALMNAMEN1TDP1ALDH1A1
SCHEMBL3211382 0.82 KMT2A (0.38) KMT2ALMNAMEN1ALDH1A1MAPT
SCHEMBL3215316 0.82 MAPT (0.34) KMT2ALMNAMEN1TDP1ALDH1A1
SCHEMBL3214866 0.81 CTSL (0.33) KMT2ALMNAMEN1TDP1ALDH1A1
SCHEMBL3199127 0.81 APEX1 (0.38) KMT2ALMNAMEN1TDP1ALDH1A1
SCHEMBL3685517 0.77 KMT2A (0.41) KMT2ALMNAMEN1TDP1ALDH1A1
SCHEMBL3210109 0.76 KMT2A (0.40) KMT2ALMNAMEN1TDP1ALDH1A1
SCHEMBL3193391 0.76 LMNA (0.38) KMT2ALMNAMEN1TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732643-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME HANAOKA HIDENORI 2010-02-25 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same HANAOKA HIDENORI 2009-02-26 US disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same C1R, C1S, AP1M1 KMT2A 2101/4885LMNA 2849/4885MEN1 1101/4885
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME C1R, C1S, AP1M1 KMT2A 2101/4885LMNA 2849/4885MEN1 1101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.