Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 4/20 | 0.89 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.89 |
| ▸ | PRMT3 | O60678 | 2/20 | 0.89 |
| ▸ | PNMT | P11086 | 2/20 | 0.89 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.89 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.89 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.89 |
| ▸ | PRMT7 | Q9NVM4 | 2/20 | 0.89 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.89 |
| ▸ | PCMT1 | P22061 | 1/20 | 0.89 |
| ▸ | KDR | P35968 | 1/20 | 0.89 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.89 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.89 |
| ▸ | AMD1 | P17707 | 5/20 | 0.78 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.60 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.60 |
| ▸ | NNMT | P40261 | 2/20 | 0.60 |
| ▸ | TRDMT1 | O14717 | 1/20 | 0.60 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.60 |
| ▸ | INMT | O95050 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ademetionine SCHEMBL29355793 | 0.94 | CARM1 (1.00) | CARM1PRMT5PRMT3PNMTPRMT6 | |
| Ademetionine SCHEMBL1300198 | 0.94 | CARM1 (1.00) | CARM1PRMT5PRMT3PNMTPRMT6 | |
| Ademetionine SCHEMBL1300205 | 0.94 | CARM1 (1.00) | CARM1PRMT5PRMT3PNMTPRMT6 | |
| Ademetionine SCHEMBL25176 | 0.94 | CARM1 (1.00) | CARM1PRMT5PRMT3PNMTPRMT6 | |
| Ademetionine SCHEMBL3208360 | 0.94 | CARM1 (0.89) | CARM1PRMT5PRMT3PNMTPRMT6 | |
| Ademetionine SCHEMBL4747876 | 0.94 | CARM1 (0.98) | CARM1PRMT5PRMT3PNMTPRMT6 | |
| Ademetionine SCHEMBL1980696 | 0.94 | CARM1 (0.98) | CARM1PRMT5PRMT3PNMTPRMT6 | |
| Ademetionine SCHEMBL8171653 | 0.92 | CARM1 (0.85) | CARM1PRMT5PRMT3PNMTPRMT6 | |
| Ademetionine SCHEMBL7802310 | 0.92 | CARM1 (0.85) | CARM1PRMT5PRMT3PNMTPRMT6 | |
| Ademetionine SCHEMBL29421543 | 0.89 | CARM1 (0.89) | CARM1PRMT5PRMT3PNMTPRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100062993-A1 | Adenosine Nucleotides as Dietary Supplements and as Agents in the Prevention of Cancer and the Metastasis Thereof | Bulka, Yochanan R. (US) | 2010-03-11 | — | — | US | disclosed |
| US-5753213-A | TREATMENT OF SCALP SEBORRHEA AND PRURITUS | BIORESEARCH S.P.A. (IT) | 1998-05-19 | — | — | US | disclosed |
| EP-0387756-B1 | Use of 5'-deoxy-5'-methylthioadenosine s-adenosylmethionine and their salts in the preparation of seborrhea-reducing pharmaceutical compositions | BIORESEARCH SPA (IT) | 1994-01-12 | — | — | EP | disclosed |
| EP-0387756-A1 | Use of 5'-deoxy-5'-methylthioadenosine s-adenosylmethionine and their salts in the preparation of seborrhea-reducing pharmaceutical compositions | BIORESEARCH S.p.A. (IT) | 1990-09-19 | — | — | EP | disclosed |