Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6215373 | 0.84 | ALDH1A1 (0.50) | CYP19A1BRD4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL3200987 | 0.82 | ALDH1A1 (0.45) | CYP19A1BRD4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL11750380 | 0.81 | LMNA (0.50) | CYP19A1BRD4KDM4EALDH1A1RAB9A | |
| SCHEMBL6212540 | 0.80 | BRD4 (0.63) | BRD4KDM4EALDH1A1HSD17B10RAB9A | |
| SCHEMBL14782205 | 0.78 | HSD17B1 (0.57) | ALDH1A1RAB9APOLBNPC1MAPT | |
| SCHEMBL8715887 | 0.78 | ALDH1A1 (0.47) | BRD4KDM4EALDH1A1HSD17B10RAB9A | |
| SCHEMBL29256012 | 0.76 | ABL1 (0.48) | BRD4KDM4EALDH1A1HSD17B10RAB9A | |
| SCHEMBL4185400 | 0.76 | CYP19A1 (0.44) | CYP19A1BRD4RAB9APOLBNPC1 | |
| SCHEMBL14391451 | 0.76 | CCR1 (0.48) | CYP19A1BRD4ALDH1A1HSD17B10RAB9A | |
| SCHEMBL27746846 | 0.76 | BRD4 (0.43) | CYP19A1BRD4RAB9APOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041905-A1 | Process for the Preparation of Substituted 2-Acetylamino-Alkoxyphenyl | ASTRAZENECA AB (SE) | 2010-02-18 | — | — | US | claimed |
| EP-2044045-A2 | A PROCESS FOR THE PREPARATION OF SUBSTITUTED 2-ACETYLAMINO-ALKOXYPHENYL | AstraZeneca AB (SE) | 2009-04-08 | — | — | EP | claimed |
| WO-2008010764-A2 | A PROCESS FOR THE PREPARATION OF SUBSTITUTED 2-ACETYLAMINO-ALKOXYPHENYL | ASTRAZENECA AB (SE) | 2008-01-24 | — | — | WO | claimed |
| US-20100041905-A1 | Process for the Preparation of Substituted 2-Acetylamino-Alkoxyphenyl | ASTRAZENECA AB (SE) | 2010-02-18 | — | — | US | disclosed |
| US-20100041905-A1 | Process for the Preparation of Substituted 2-Acetylamino-Alkoxyphenyl | ASTRAZENECA AB (SE) | 2010-02-18 | — | — | US | disclosed |
| US-20100041905-A1 | Process for the Preparation of Substituted 2-Acetylamino-Alkoxyphenyl | ASTRAZENECA AB (SE) | 2010-02-18 | — | — | US | disclosed |
| WO-2008010764-A2 | A PROCESS FOR THE PREPARATION OF SUBSTITUTED 2-ACETYLAMINO-ALKOXYPHENYL | ASTRAZENECA AB (SE) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041905-A1 | Process for the Preparation of Substituted 2-Acetylamino-Alkoxyphenyl | F12, RPS4Y1, CCNA1 | CYP19A1 75/4885BRD4 2714/4885KDM4E 989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.