SCHEMBL3209323

SCHEMBL3209323

Cc1ccc(C(=O)c2[c]ccc(C)c2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.54
LMNA P02545 2/20 0.54
SRD5A2 P31213 2/20 0.47
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
AKR1C3 P42330 1/20 0.41
HTT P42858 4/20 0.40
MAPT P10636 3/20 0.40
GAA P10253 2/20 0.40
RAB9A P51151 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PKM P14618 2/20 0.39
ATM Q13315 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
HPGD P15428 1/20 0.39
NLRP1 Q9C000 1/20 0.39
MEN1 O00255 1/20 0.39
NTSR1 P30989 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16601079 0.87 ALDH1A1 (0.45) ALDH1A1SRD5A2CES2CES1SMN1; SMN2
SCHEMBL6447649 0.82 ALDH1A1 (0.46) ALDH1A1LMNASRD5A2CES2CES1
SCHEMBL315202 0.78 ALDH1A1 (0.54) ALDH1A1LMNASRD5A2CES2CES1
SCHEMBL3735378 0.76 CSNK2A1 (0.41) ALDH1A1SRD5A2SMN1; SMN2MEN1KMT2A
SCHEMBL11336223 0.76 CYP2A6 (0.38) ALDH1A1LMNASMN1; SMN2MAPTRAB9A
SCHEMBL10969650 0.75 CTBP2 (0.32) ALDH1A1TDP1
SCHEMBL52200 0.72 ALDH1A1 (1.00) ALDH1A1LMNASRD5A2CES2CES1
SCHEMBL822185 0.72 ALDH1A1 (1.00) ALDH1A1LMNASRD5A2CES2CES1
SCHEMBL11088791 0.72 TDP1 (0.44) ALDH1A1SMN1; SMN2MAPTGAAL3MBTL1
SCHEMBL12362778 0.71 ALDH1A1 (0.84) ALDH1A1LMNASRD5A2CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9223211-B2 Photosensitive resin compositions, processes for preparing cured films, the resulting cured films, organic EL display devices and liquid crystal display devices FUJIFILM CORPORATION (JP) 2015-12-29 US disclosed
US-20150148546-A1 PHOTOSENSITIVE RESIN COMPOSITIONS, PROCESSES FOR PREPARING CURED FILMS, THE RESULTING CURED FILMS, ORGANIC EL DISPLAY DEVICES AND LIQUID CRYSTAL DISPLAY DEVICES FUJIFILM CORPORATION (JP) 2015-05-28 US disclosed
US-20120165409-A1 WRINKLE-IMPROVING AGENT SHISEIDO COMPANY, LTD. (JP) 2012-06-28 US disclosed
US-20100035881-A1 WRINKLE-IMPROVING AGENT SHISEIDO COMPANY, LTD. (JP) 2010-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100035881-A1 WRINKLE-IMPROVING AGENT AAAS, GLA, COL14A1 ALDH1A1 1501/4885LMNA 133/4885SRD5A2 4404/4885
US-20120165409-A1 WRINKLE-IMPROVING AGENT AAAS, GLA, COL14A1 ALDH1A1 1151/4885LMNA 105/4885SRD5A2 4242/4885
US-20150148546-A1 PHOTOSENSITIVE RESIN COMPOSITIONS, PROCESSES FOR PREPARING CURED FILMS, THE RESULTING CURED FILMS, ORGANIC EL DISPLAY DEVICES AND LIQUID CRYSTAL DISPLAY DEVICES LCP1, ARCN1, RARA ALDH1A1 81/4885LMNA 1436/4885SRD5A2 1757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.