Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3209323 | 0.82 | ALDH1A1 (0.54) | ALDH1A1LMNASRD5A2CNR1CNR2 | |
| SCHEMBL26490140 | 0.74 | ALDH1A1 (0.70) | ALDH1A1LMNASRD5A2CNR1CNR2 | |
| SCHEMBL24600462 | 0.72 | MAPT (0.59) | ALDH1A1LMNASRD5A2SMN1; SMN2HTT | |
| SCHEMBL315202 | 0.71 | ALDH1A1 (0.54) | ALDH1A1LMNASRD5A2CES2CES1 | |
| SCHEMBL16601079 | 0.70 | ALDH1A1 (0.45) | ALDH1A1SRD5A2CNR1CNR2CES2 | |
| SCHEMBL564584 | 0.68 | LMNA (0.34) | ALDH1A1LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL28727133 | 0.66 | ALDH1A1 (0.70) | ALDH1A1LMNASRD5A2CNR1CNR2 | |
| SCHEMBL52200 | 0.66 | ALDH1A1 (1.00) | ALDH1A1LMNASRD5A2CES2CES1 | |
| SCHEMBL822185 | 0.66 | ALDH1A1 (1.00) | ALDH1A1LMNASRD5A2CES2CES1 | |
| SCHEMBL28787119 | 0.66 | CNR1 (0.55) | ALDH1A1LMNASRD5A2CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050043369-A1 | Bactericidal antimicrobial methods and compositions for use in treating gram positive infections | PROTEZ PHARMACEUTICALS INC. (US) | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043369-A1 | Bactericidal antimicrobial methods and compositions for use in treating gram positive infections | NAAA, TLR8, OPA1 | ALDH1A1 2191/4885LMNA 3860/4885SRD5A2 3648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.