Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 6/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 6/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | CFD | P00746 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13490211 | 0.80 | TAS1R3 (0.41) | PDE10ATAS1R3TAS1R1TAS1R2MEN1 | |
| SCHEMBL13490305 | 0.79 | PDE10A (0.44) | PDE10AMAOBTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3209469 | 0.79 | PDE10A (0.41) | PDE10AMAOBTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL13490214 | 0.77 | SMN1; SMN2 (0.41) | PDE10AMAOBMAOAMEN1MAPT | |
| SCHEMBL13490234 | 0.77 | KMT2A (0.41) | PDE10AMAOBTAS1R3TAS1R1ACHE | |
| SCHEMBL13490276 | 0.76 | PDE10A (0.36) | PDE10AMAOBTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL13490235 | 0.76 | PDE10A (0.40) | PDE10ATAS1R3TAS1R1TAS1R2MEN1 | |
| SCHEMBL13490220 | 0.75 | KMT2A (0.39) | PDE10AMAOBMAOAMEN1MAPT | |
| SCHEMBL13490210 | 0.75 | L3MBTL1 (0.42) | PDE10ATAS1R3TAS1R1TAS1R2MEN1 | |
| SCHEMBL13490242 | 0.75 | PDE10A (0.48) | PDE10ATAS1R3TAS1R1TAS1R2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048699-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | claimed |
| US-20100048699-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| EP-2043444-A1 | CHEMICAL COMPOUNDS | Syngenta Limited (GB) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008009881-A1 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED. (GB) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048699-A1 | CHEMICAL COMPOUNDS | ACHE, TYR, SGMS1 | PDE10A 1000/4885MAOB 814/4885TAS1R3 816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.