Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.40 |
| ▸ | APEX1 | P27695 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL759457 | 1.00 | — | — | |
| Bromide SCHEMBL3209601 | 0.95 | — | — | |
| Bromide SCHEMBL28199851 | 0.95 | — | — | |
| SCHEMBL232317 | 0.94 | — | — | |
| Fluoride Ion SCHEMBL1812697 | 0.89 | — | — | |
| Iodide SCHEMBL196407 | 0.89 | — | — | |
| Water SCHEMBL187547 | 0.89 | — | — | |
| Water SCHEMBL28331162 | 0.89 | NFKB1 (0.42) | NFKB1TSHRKCNA1MEN1KMT2A | |
| Bromide SCHEMBL3209609 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL370134 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283509-A4 | THE CONTROL OF BIOFOULING IN AQUEOUS SYSTEMS BY NON-POLYMERIC QUATERNARY AMMONIUM POLYHALIDES. | GREAT LAKES CHEMICAL CORP (US) | 1989-04-12 | — | — | EP | claimed |
| EP-0283509-A1 | THE CONTROL OF BIOFOULING IN AQUEOUS SYSTEMS BY NON-POLYMERIC QUATERNARY AMMONIUM POLYHALIDES. | GREAT LAKES CHEMICAL CORP (US) | 1988-09-28 | — | — | EP | claimed |
| WO-1988002351-A1 | THE CONTROL OF BIOFOULING IN AQUEOUS SYSTEMS BY NON-POLYMERIC QUATERNARY AMMONIUM POLYHALIDES | GREAT LAKES CHEMICAL CORPORATION (US) | 1988-04-07 | — | — | WO | claimed |
| US-9629376-B2 | Microbiocidal treatment of edible fruits and vegetables | ALBEMARLE CORPORATION (US) | 2017-04-25 | — | — | US | disclosed |
| US-20130129843-A1 | Microbiocidal Treatment Of Edible Fruits And Vegetables | ALBEMARLE CORPORATION (US) | 2013-05-23 | — | — | US | disclosed |
| US-20100035950-A1 | Microbiocidal Treatment Of Edible Fruits And Vegetables | ALBEMARLE CORPORATION (US) | 2010-02-11 | — | — | US | disclosed |
| US-4978685-A | MIXED WITH SURFACTANTS; PROVIDING OXIDIZING HALOGEN AND NON-OXIDIZING QUATERNARY MONOHALIDE FORM | GREAT LAKES CHEMICAL CORPORATION (US) | 1990-12-18 | — | — | US | disclosed |
| US-4976874-A | REDUCIBLE POLYHALIDE ANTIFOULING AGENTS WHICH RELEASE OXIDIZING HALOGENS | GREAT LAKES CHEMICAL CORPORATION (US) | 1990-12-11 | — | — | US | disclosed |
| EP-0283509-A4 | THE CONTROL OF BIOFOULING IN AQUEOUS SYSTEMS BY NON-POLYMERIC QUATERNARY AMMONIUM POLYHALIDES. | GREAT LAKES CHEMICAL CORP (US) | 1989-04-12 | — | — | EP | disclosed |
| EP-0283509-A1 | THE CONTROL OF BIOFOULING IN AQUEOUS SYSTEMS BY NON-POLYMERIC QUATERNARY AMMONIUM POLYHALIDES. | GREAT LAKES CHEMICAL CORP (US) | 1988-09-28 | — | — | EP | disclosed |
| WO-1988002351-A1 | THE CONTROL OF BIOFOULING IN AQUEOUS SYSTEMS BY NON-POLYMERIC QUATERNARY AMMONIUM POLYHALIDES | GREAT LAKES CHEMICAL CORPORATION (US) | 1988-04-07 | — | — | WO | disclosed |