SCHEMBL3209896

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3223356	0.93	THRB (0.39)	THRBTHRAKDM4EKMT2A
	SCHEMBL3222342	0.90	THRB (0.39)	THRBTHRALMNAMAPTALDH1A1
	SCHEMBL3231997	0.90	THRB (0.39)	THRBTHRALMNAMAPTKDM4E
	SCHEMBL3228053	0.88	THRB (0.39)	THRBTHRAKDM4EKMT2A
	SCHEMBL3225681	0.87	THRB (0.42)	THRBTHRALMNAMAPTKDM4E
	SCHEMBL3955670	0.86	LMNA (0.36)	THRBTHRALMNAKDM4EHPGD
	SCHEMBL3219157	0.85	THRB (0.37)	THRBTHRALMNAHTTSMN1; SMN2
	SCHEMBL3232815	0.84	THRB (0.38)	THRBTHRAMAPTKDM4EKMT2A
	SCHEMBL3230608	0.83	THRB (0.41)	THRBTHRA
	SCHEMBL3230598	0.83	KCNK3 (0.38)	THRBMAPTHTTKMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.