Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14040822 | 1.00 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1PDE10AALPL | |
| SCHEMBL1999695 | 0.88 | KMT2A (0.46) | ALDH1A1KMT2AMEN1PDE10AALPL | |
| SCHEMBL14040995 | 0.85 | PDE10A (0.46) | ALDH1A1KMT2AMEN1PDE10AALPL | |
| SCHEMBL13490305 | 0.81 | PDE10A (0.44) | ALDH1A1KMT2AMEN1PDE10AALPL | |
| SCHEMBL4700260 | 0.80 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1ALPLALPI | |
| SCHEMBL3219943 | 0.80 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1ALPLALPI | |
| SCHEMBL13490295 | 0.78 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1PDE10AALPL | |
| SCHEMBL13490201 | 0.78 | KMT2A (0.44) | ALDH1A1KMT2AMEN1PDE10AMAPT | |
| SCHEMBL13490278 | 0.77 | TAAR1 (0.41) | ALDH1A1KMT2AMEN1PDE10ATAS1R3 | |
| SCHEMBL13490249 | 0.77 | TRPM8 (0.39) | ALDH1A1KMT2AMEN1PDE10AALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048699-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| EP-2043444-A1 | CHEMICAL COMPOUNDS | Syngenta Limited (GB) | 2009-04-08 | — | — | EP | disclosed |
| EP-2019095-A1 | Iminooxazole and iminothiazole compounds as pesticides | Bayer CropScience AG (DE) | 2009-01-28 | — | — | EP | disclosed |
| EP-2019095-A1 | Iminooxazole and iminothiazole compounds as pesticides | Bayer CropScience AG (DE) | 2009-01-28 | — | — | EP | disclosed |
| WO-2009007022-A2 | IMINOOXAZOLE AND IMINOTHIAZOLE COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2009-01-15 | — | — | WO | disclosed |
| WO-2009007022-A2 | IMINOOXAZOLE AND IMINOTHIAZOLE COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2009-01-15 | — | — | WO | disclosed |
| EP-1977646-A1 | Insecticidal hydroxyethyl thlourea derivatives | Bayer CropScience AG (DE) | 2008-10-08 | — | — | EP | disclosed |
| WO-2008009881-A1 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED. (GB) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048699-A1 | CHEMICAL COMPOUNDS | ACHE, TYR, SGMS1 | ALDH1A1 128/4885KMT2A 2630/4885MEN1 316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.