Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 6/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | TEK | Q02763 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.31 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.31 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.31 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3224938 | 0.95 | HDAC1 (0.36) | HDAC1LCKS1PR3KDRTEK | |
| SCHEMBL3777934 | 0.94 | KCNQ3 (0.33) | HDAC1S1PR3MAPTNPSR1KCNQ3 | |
| SCHEMBL3701195 | 0.93 | LCK (0.39) | HDAC1LCKS1PR3KDRTEK | |
| SCHEMBL3213487 | 0.90 | KDM4E (0.34) | HDAC1GRM5KCNQ3KCNQ2KCNE1 | |
| SCHEMBL3695537 | 0.89 | KCNQ3 (0.35) | S1PR3MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL3219952 | 0.89 | KCNQ3 (0.35) | HDAC1S1PR3MAPTNPSR1KCNQ3 | |
| SCHEMBL3011716 | 0.88 | LCK (0.41) | HDAC1LCKS1PR3KDRTEK | |
| SCHEMBL3217239 | 0.87 | KDM4E (0.35) | HDAC1LCKS1PR3KDRTEK | |
| SCHEMBL3715668 | 0.87 | PKM (0.41) | HDAC1S1PR3MAPTHTT | |
| SCHEMBL3221010 | 0.85 | MAPT (0.39) | NPC1RAB9AMEN1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120556-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-09 | — | — | EP | disclosed |
| US-8389766-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-05 | — | — | US | disclosed |
| US-20100056639-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056639-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, NIT2 | HDAC1 234/4885LCK 4621/4885S1PR3 867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.