Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | LCK | P06239 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | TEK | Q02763 | 2/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.31 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.31 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3220253 | 0.95 | KDM4E (0.40) | KDM4EALDH1A1HDAC1LMNAGRM5 | |
| SCHEMBL3701195 | 0.92 | LCK (0.39) | MAPTHDAC1LCKS1PR3GRM5 | |
| SCHEMBL1420650 | 0.91 | S1PR3 (0.40) | KDM4EALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL3224891 | 0.91 | HDAC1 (0.35) | KDM4EALDH1A1HPGDHSD17B10HDAC1 | |
| SCHEMBL3213487 | 0.91 | KDM4E (0.34) | KDM4EALDH1A1HDAC1GRM5AR | |
| SCHEMBL3226663 | 0.90 | ALDH1A1 (0.42) | KDM4EALDH1A1MAPTHPGDHDAC1 | |
| SCHEMBL289387 | 0.90 | KCNJ11 (0.36) | KDM4EALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL3210164 | 0.87 | HDAC1 (0.34) | MAPTHDAC1LCKSMN1; SMN2S1PR3 | |
| SCHEMBL3011716 | 0.87 | LCK (0.41) | MAPTHDAC1LCKS1PR3KDR | |
| SCHEMBL1275178 | 0.86 | S1PR3 (0.42) | KDM4EALDH1A1MAPTHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106242998-B | Use of 4-cyano-3-benzoylamino-N-phenyl-benzamides in pesticides | 先正达参股股份有限公司 | 2021-11-05 | — | — | CN | disclosed |
| EP-2120556-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-09 | — | — | EP | disclosed |
| EP-2427427-B1 | 4-CYANO-3-BENZOYLAMINO-N-PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | SYNGENTA PARTICIPATIONS AG (CH) | 2013-12-25 | — | — | EP | disclosed |
| US-8431514-B2 | 4-cyano-3-benzoylamino-N-phenyl-benzamides for use in pest control | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-30 | — | — | US | disclosed |
| US-8389766-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-05 | — | — | US | disclosed |
| US-8247594-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2012-08-21 | — | — | US | disclosed |
| US-20120122975-A1 | 4-CYANO-3-BENZOYLAMINO-N-PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-17 | — | — | US | disclosed |
| US-20100130601-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-05-27 | — | — | US | disclosed |
| US-20100056639-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130601-A1 | INSECTICIDAL COMPOUNDS | ACHE, NIT2, CHRM1 | KDM4E 3298/4885ALDH1A1 146/4885MAPT 4101/4885 |
| US-20120122975-A1 | 4-CYANO-3-BENZOYLAMINO-N-PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | NISCH, AADAC, ACHE | KDM4E 270/4885ALDH1A1 989/4885MAPT 3060/4885 |
| US-20100056639-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, NIT2 | KDM4E 2732/4885ALDH1A1 122/4885MAPT 3612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.