Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.45 |
| ▸ | GID4 | Q8IVV7 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13490643 | 0.94 | PIN1 (0.47) | PIN1GID4NPC1RAB9AKMT2A | |
| Trifluoroacetic Acid SCHEMBL3210512 | 0.83 | HTR2B (0.43) | PIN1GID4SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3216310 | 0.82 | KDM4E (0.49) | NPC1RAB9AKMT2ATHRB | |
| Trifluoroacetic Acid SCHEMBL3210746 | 0.82 | SMN1; SMN2 (0.47) | GID4RAB9AKMT2ASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3208139 | 0.81 | CHRM4 (0.43) | NPC1RAB9ACHRNA7SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3216470 | 0.81 | HTR2B (0.43) | GID4NPC1RAB9ASMN1; SMN2PAX8 | |
| Trifluoroacetic Acid SCHEMBL3222205 | 0.80 | MLLT1 (0.54) | NPC1RAB9ATHRB | |
| Trifluoroacetic Acid SCHEMBL3224994 | 0.80 | MLLT1 (0.54) | NPC1RAB9ATHRB | |
| Trifluoroacetic Acid SCHEMBL3211115 | 0.80 | TNKS (0.42) | GID4CHRNA7 | |
| Trifluoroacetic Acid SCHEMBL3219974 | 0.80 | EPHX2 (0.47) | GID4SMN1; SMN2PAX8ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | ACIN1, HAT1, CCNE1 | PIN1 3959/4885GID4 2961/4885NPC1 3250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.