Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 4/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | GID4 | Q8IVV7 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13490684 | 0.94 | EPHX2 (0.50) | EPHX2TAS1R3TAS1R1TAS1R2HTR2B | |
| Trifluoroacetic Acid SCHEMBL3216470 | 0.90 | HTR2B (0.43) | HTR2BCHEK1CXCR6PAX8GID4 | |
| Trifluoroacetic Acid SCHEMBL3210512 | 0.90 | HTR2B (0.43) | HTR2BCHEK1CXCR6GID4SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3218339 | 0.88 | CXCR6 (0.42) | HTR2BCHEK1CXCR6PAX8GID4 | |
| Trifluoroacetic Acid SCHEMBL3222284 | 0.87 | RAB9A (0.48) | HTR2BCHEK1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3202683 | 0.87 | RAB9A (0.48) | TAS1R3TAS1R1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3223330 | 0.87 | SMYD3 (0.44) | HTR2BCHEK1CXCR6GID4SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3221433 | 0.87 | SMYD3 (0.44) | HTR2BCHEK1CXCR6GID4SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3223613 | 0.86 | FOXO1 (0.45) | HTR2BCHEK1CXCR6PAX8 | |
| Trifluoroacetic Acid SCHEMBL3222205 | 0.86 | MLLT1 (0.54) | HTR2BCHEK1CXCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | ACIN1, HAT1, CCNE1 | EPHX2 4250/4885TAS1R3 234/4885TAS1R1 305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.