SCHEMBL321112

SCHEMBL321112

CC(CC(=O)OC(=N)CCC(=O)OC(=O)CC(C)SSc1ccccn1)SSc1ccccn1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.38
ALDH1A1 P00352 6/20 0.36
EHMT2 Q96KQ7 1/20 0.36
EHMT1 Q9H9B1 1/20 0.36
APOBEC3G Q9HC16 1/20 0.36
SMN1; SMN2 Q16637 6/20 0.35
HPGD P15428 5/20 0.35
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
TSHR P16473 1/20 0.35
HSD17B10 Q99714 1/20 0.34
RAB9A P51151 3/20 0.34
NPC1 O15118 1/20 0.34
MAPT P10636 2/20 0.34
PKM P14618 1/20 0.34
MAPK10 P53779 1/20 0.33
POLB P06746 1/20 0.33
RGS12 O14924 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1655486 0.91 LMNA (0.38) LMNAALDH1A1EHMT2EHMT1APOBEC3G
SCHEMBL16167268 0.83 LMNA (0.41) LMNAALDH1A1EHMT2EHMT1APOBEC3G
SCHEMBL12814052 0.81 SMN1; SMN2 (0.41) LMNAALDH1A1SMN1; SMN2HPGDKMT2A
SCHEMBL110223 0.80 ALDH1A1 (0.46) LMNAALDH1A1EHMT2EHMT1APOBEC3G
SCHEMBL2409030 0.79 LMNA (0.35) LMNAALDH1A1EHMT2EHMT1APOBEC3G
SCHEMBL906682 0.78 ALDH1A1 (0.41) LMNAALDH1A1EHMT2EHMT1APOBEC3G
SCHEMBL8196222 0.78 ALDH1A1 (0.37) LMNAALDH1A1EHMT2EHMT1APOBEC3G
SCHEMBL2169206 0.77 LMNA (0.35) LMNAALDH1A1SMN1; SMN2HPGDKMT2A
SCHEMBL5665047 0.77 ALDH1A1 (0.58) LMNAALDH1A1SMN1; SMN2HPGDKMT2A
SCHEMBL8609493 0.76 ALDH1A1 (0.49) LMNAALDH1A1EHMT2EHMT1APOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388650-A1 OLIGO-TRAP FUSION PROTEINS (OFPs) AND USES THEREOF ENOSI THERAPEUTICS CORP (US) 2025-12-25 US disclosed
US-20240197853-A1 MULTIVALENT CHOLERA MULTIEPITOPE FUSION ANTIGEN (MEFA) AND METHODS OF USE THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2024-06-20 US disclosed
US-20240115686-A1 SHIGELLA MULTI-EPITOPE FUSION ANTIGEN PROTEINS AND METHODS OF USE THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2024-04-11 US disclosed
WO-2023168426-A1 COMPOSITIONS AND CELLS CONTAINING MIXTURES OF OLIGO-TRAP FUSION PROTEINS (OFPS) AND USES THEREOF ENOSI THERAPEUTICS CORPORATION (US) 2023-09-07 WO disclosed
US-11725041-B2 Immune-modulating compounds THE COUNCIL OF THE QUEENSLAND INSTITUTE OF MEDICAL RESEARCH (AU) 2023-08-15 US disclosed
US-20230203470-A1 COMPOSITIONS OF ADENOSINE DEAMINASE-2 (ADA2), VARIANTS THEREOF AND METHODS OF USING SAME DADA2 FOUNDATION 2023-06-29 US disclosed
US-11584923-B2 Compositions of adenosine deaminase-2 (ADA2), variants thereof and methods of using same HALOZYME, INC. (US) 2023-02-21 US disclosed
US-11529389-B2 Delivering biological drugs to tissues University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2022-12-20 US disclosed
WO-2022216734-A1 MULTIVALENT CHOLERA MULTIEPITOPE FUSION ANTIGEN (MEFA) AND METHODS OF USE THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2022-10-13 WO disclosed
WO-2021076610-A1 SHIGELLA MULTI-EPITOPE FUSION ANTIGEN PROTEINS AND METHODS OF USE THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2021-04-22 WO disclosed
WO-1998026277-A2 APPARATUS AND METHOD FOR DETECTING AND IDENTIFYING INFECTIOUS AGENTS PROLUME, LTD. (US) 1998-06-18 WO disclosed
WO-1997049434-A9 HEPARINIZED MEDICAL DEVICES CONTAINING HEPARIN-BINDING GROWTH FACTOR CONJUGATES 1998-05-07 WO disclosed
EP-0833665-A1 COMPOSITIONS CONTAINING NUCLEIC ACIDS AND LIGANDS FOR THERAPEUTIC TREATMENT PRIZM PHARMACEUTICALS, INC. (US) 1998-04-08 EP disclosed
WO-1997049434-A2 HEPARINIZED MEDICAL DEVICES CONTAINING HEPARIN-BINDING GROWTH FACTOR CONJUGATES PRIZM PHARMACEUTICALS, INC. (US) 1997-12-31 WO disclosed
EP-0776218-A2 HEPARIN-BINDING GROWTH FACTORS FOR GENE THERAPY AND ANTERIOR EYE DISORDERS PRIZM PHARMACEUTICALS, INC. (US) 1997-06-04 EP disclosed
WO-1996036362-A1 COMPOSITIONS CONTAINING NUCLEIC ACIDS AND LIGANDS FOR THERAPEUTIC TREATMENT PRIZM PHARMACEUTICALS, INC. (US) 1996-11-21 WO disclosed
US-5536820-A Avidin-binding azo reagents E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-07-16 US disclosed
WO-1996008274-A2 CONJUGATES OF HEPARIN-BINDING EPIDERMAL GROWTH FACTOR-LIKE GROWTH FACTOR WITH TARGETED AGENTS PRIZM PHARMACEUTICALS, INC. (US) 1996-03-21 WO disclosed
WO-1996006641-A1 CONJUGATES OF VASCULAR ENDOTHELIAL GROWTH FACTOR WITH TARGETED AGENTS PRIZM PHARMACEUTICALS, INC. (US) 1996-03-07 WO disclosed
WO-1995024928-A2 HEPARIN-BINDING GROWTH FACTORS FOR GENE THERAPY AND ANTERIOR EYE DISORDERS PRIZM PHARMACEUTICALS, INC. (US) 1995-09-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11584923-B2 Compositions of adenosine deaminase-2 (ADA2), variants thereof and methods of using same ADA, CDA, ADAR LMNA 2327/4885ALDH1A1 339/4885EHMT2 976/4885
US-20230203470-A1 COMPOSITIONS OF ADENOSINE DEAMINASE-2 (ADA2), VARIANTS THEREOF AND METHODS OF USING SAME ADA, CDA, ADAR LMNA 2327/4885ALDH1A1 339/4885EHMT2 976/4885
US-20250388650-A1 OLIGO-TRAP FUSION PROTEINS (OFPs) AND USES THEREOF TNFSF11, TNFRSF9, FCER2 LMNA 4558/4885ALDH1A1 4843/4885EHMT2 3200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.