Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3205795 | 0.82 | HSD17B10 (0.39) | HSD17B10KDM4EAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL13541671 | 0.80 | HSD17B10 (0.38) | HSD17B10KDM4EALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL13300851 | 0.78 | HSD17B10 (0.40) | HSD17B10KDM4EAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL13489631 | 0.78 | HSD17B10 (0.36) | HSD17B10ALDH1A1CYP2D6MMP1MMP9 | |
| SCHEMBL11983653 | 0.78 | HSD17B10 (0.36) | HSD17B10KDM4E | |
| SCHEMBL3211571 | 0.77 | HSD17B10 (0.39) | HSD17B10KDM4EAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL639796 | 0.77 | AKR1C4 (0.39) | HSD17B10KDM4EAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL29562450 | 0.75 | KDM4E (0.49) | HSD17B10KDM4EAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL1119372 | 0.75 | KDM4E (0.49) | HSD17B10KDM4EAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL640590 | 0.75 | ALDH1A1 (0.44) | HSD17B10AKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785646-B2 | Process for producing amide compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-07-22 | — | — | US | disclosed |
| US-8541613-B2 | Process for producing amide compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-09-24 | — | — | US | disclosed |
| US-8501951-B2 | Process for producing amide compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-08-06 | — | — | US | disclosed |
| US-20130131349-A1 | PROCESS FOR PRODUCING AMIDE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-05-23 | — | — | US | disclosed |
| US-20130131371-A1 | PROCESS FOR PRODUCING AMIDE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-05-23 | — | — | US | disclosed |
| US-20130131348-A1 | PROCESS FOR PRODUCING AMIDE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-05-23 | — | — | US | disclosed |
| EP-2143721-B1 | HYDRAZIDE COMPOUND AND HARMFUL ARTHROPOD-CONTROLLING AGENT CONTAINING THE SAME | SUMITOMO CHEMICAL CO (JP) | 2012-08-15 | — | — | EP | disclosed |
| US-8119811-B2 | Method for producing amide compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-21 | — | — | US | disclosed |
| US-8119811-B2 | Method for producing amide compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-21 | — | — | US | disclosed |
| US-20100113794-A1 | METHOD FOR PRODUCING AMIDE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-05-06 | — | — | US | disclosed |
| US-20100113794-A1 | METHOD FOR PRODUCING AMIDE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-05-06 | — | — | US | disclosed |
| US-20100048640-A1 | HYDRAZIDE COMPOUND AND HARMFUL ARTHROPOD-CONTROLLING AGENT CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-02-25 | — | — | US | disclosed |
| EP-2143721-A1 | HYDRAZIDE COMPOUND AND HARMFUL ARTHROPOD-CONTROLLING AGENT CONTAINING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2010-01-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131349-A1 | PROCESS FOR PRODUCING AMIDE COMPOUND | C9, F3, C5 | HSD17B10 1616/4885KDM4E 2417/4885AKR1C4 413/4885 |
| US-20130131371-A1 | PROCESS FOR PRODUCING AMIDE COMPOUND | C9, F3, C5 | HSD17B10 1616/4885KDM4E 2417/4885AKR1C4 413/4885 |
| US-20100048640-A1 | HYDRAZIDE COMPOUND AND HARMFUL ARTHROPOD-CONTROLLING AGENT CONTAINING THE SAME | CYC1, L3MBTL1, CBR3 | HSD17B10 2530/4885KDM4E 2227/4885AKR1C4 563/4885 |
| US-20130131348-A1 | PROCESS FOR PRODUCING AMIDE COMPOUND | C9, F3, C5 | HSD17B10 1616/4885KDM4E 2417/4885AKR1C4 413/4885 |
| US-20100113794-A1 | METHOD FOR PRODUCING AMIDE COMPOUND | CBR3, AOX1, AOC2 | HSD17B10 499/4885KDM4E 2739/4885AKR1C4 180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.