SCHEMBL3211679

SCHEMBL3211679

CC1=C(C)CC(CC(=NNc2ccc3ccccc3c2)c2ccccc2)=C1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.40
MAPT P10636 6/20 0.40
GAA P10253 6/20 0.40
KDM4E B2RXH2 5/20 0.40
SMN1; SMN2 Q16637 5/20 0.40
TDP1 Q9NUW8 4/20 0.40
LMNA P02545 4/20 0.40
HPGD P15428 3/20 0.40
HTT P42858 3/20 0.40
THRB P10828 1/20 0.40
CA1 P00915 4/20 0.37
CA2 P00918 4/20 0.37
CA4 P22748 3/20 0.37
CA9 Q16790 3/20 0.37
APEX1 P27695 1/20 0.37
KMT2A Q03164 8/20 0.37
MEN1 O00255 7/20 0.37
NPC1 O15118 6/20 0.37
RAB9A P51151 5/20 0.36
MRGPRX4 Q96LA9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3214606 0.87 GAA (0.46) ALDH1A1MAPTGAAKDM4ESMN1; SMN2
SCHEMBL3214046 0.82 ALDH1A1 (0.40) ALDH1A1MAPTGAAKDM4ESMN1; SMN2
SCHEMBL3202896 0.82 ALDH1A1 (0.40) ALDH1A1MAPTGAAKDM4ESMN1; SMN2
SCHEMBL3199470 0.81 ALDH1A1 (0.42) ALDH1A1MAPTGAAKDM4ESMN1; SMN2
SCHEMBL3212263 0.81 MAPT (0.37) ALDH1A1MAPTGAAKDM4ESMN1; SMN2
SCHEMBL3202066 0.80 MAPT (0.37) ALDH1A1MAPTGAAKDM4ESMN1; SMN2
SCHEMBL3199639 0.79 MRGPRX4 (0.40) ALDH1A1MAPTGAAKDM4ESMN1; SMN2
SCHEMBL3199430 0.79 ALDH1A1 (0.40) ALDH1A1MAPTGAAKDM4ESMN1; SMN2
SCHEMBL3203035 0.78 LMNA (0.39) ALDH1A1MAPTGAAKDM4ESMN1; SMN2
SCHEMBL3208640 0.77 ALDH1A1 (0.40) ALDH1A1MAPTGAAKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732643-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME HANAOKA HIDENORI 2010-02-25 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same HANAOKA HIDENORI 2009-02-26 US disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same C1R, C1S, AP1M1 ALDH1A1 1229/4885MAPT 2641/4885GAA 4642/4885
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME C1R, C1S, AP1M1 ALDH1A1 1229/4885MAPT 2641/4885GAA 4642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.