SCHEMBL3212419

SCHEMBL3212419

COc1ccc(-c2ncc(C)nc2C)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
JAK3 P52333 1/20 0.54
DYRK1A Q13627 1/20 0.50
KMT2A Q03164 2/20 0.49
ALDH1A1 P00352 3/20 0.47
HPGD P15428 2/20 0.47
KDM4E B2RXH2 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
LMNA P02545 1/20 0.46
SYK P43405 1/20 0.45
AURKB Q96GD4 1/20 0.45
INCENP Q9NQS7 1/20 0.45
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
PTGS2 P35354 1/20 0.44
CASP3 P42574 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
MAPT P10636 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29476058 0.98 JAK3 (0.53) JAK3DYRK1AKMT2AALDH1A1HPGD
SCHEMBL28068098 0.98 JAK3 (0.53) JAK3DYRK1AKMT2AALDH1A1HPGD
SCHEMBL10508434 0.87 ALDH1A1 (0.51) DYRK1AKMT2AALDH1A1HPGDKDM4E
SCHEMBL11375323 0.83 KMT2A (0.54) DYRK1AKMT2AALDH1A1HPGDKDM4E
SCHEMBL3419221 0.82 JAK3 (0.50) JAK3DYRK1AALDH1A1KDM4ENPSR1
SCHEMBL2120831 0.81 JAK3 (0.50) JAK3NPC1RAB9A
SCHEMBL3415089 0.80 JAK3 (0.53) JAK3DYRK1AALDH1A1HPGDKDM4E
SCHEMBL11887168 0.78 JAK3 (0.58) JAK3KMT2AALDH1A1KDM4ENPSR1
SCHEMBL4752099 0.78 JAK3 (0.57) JAK3KMT2AKDM4ENPC1RAB9A
SCHEMBL3335530 0.77 JAK3 (0.56) JAK3KMT2AALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102637830-B Light-emitting component, display device, illuminator and its manufacture method 株式会社半导体能源研究所 2017-03-01 CN disclosed
CN-102573165-B Solid-state light emitting element, light-emitting device and illuminator 株式会社半导体能源研究所 2016-06-22 CN disclosed
US-9356250-B2 Light-emitting element, comprising an organometallic complex light-emitting material, a light-emitting device and an electronic device comprising the light-emitting element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-05-31 US disclosed
US-9356250-B2 Light-emitting element, comprising an organometallic complex light-emitting material, a light-emitting device and an electronic device comprising the light-emitting element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-05-31 US disclosed
US-9356250-B2 Light-emitting element, comprising an organometallic complex light-emitting material, a light-emitting device and an electronic device comprising the light-emitting element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-05-31 US disclosed
US-8598785-B2 Organometallic complex, and light-emitting element, light-emitting device, electronic device, and lighting device using the organometallic complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD (JP) 2013-12-03 US disclosed
CN-103416106-A Light-emitting element, light-emitting device, and manufacturing method of light-emitting element SEMICONDUCTOR ENERGY LAB 2013-11-27 CN disclosed
US-20120280220-A1 Organometallic Complex, and Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device Using the Organometallic Complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-11-08 US disclosed
CN-102637830-A Light-emitting element, display device, lighting device, and method for manufacturing the same SEMICONDUCTOR ENERGY LAB 2012-08-15 CN disclosed
US-8227975-B2 Organometallic complex, and light-emitting element, light-emitting device, electronic device, and lighting device using the organometallic complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-07-24 US disclosed
US-20100181905-A1 Organometallic Complex, and Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device Using the Organometallic Complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-07-22 US disclosed
US-20100059741-A1 Light-Emitting Element, Light-Emitting Device, and Electronic Device Semiconductor Energy Laboratorry Co, Ltd. 2010-03-11 US disclosed
WO-2010026859-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-03-11 WO disclosed
US-20100059741-A1 Light-Emitting Element, Light-Emitting Device, and Electronic Device Semiconductor Energy Laboratorry Co, Ltd. 2010-03-11 US disclosed
US-20100059741-A1 Light-Emitting Element, Light-Emitting Device, and Electronic Device Semiconductor Energy Laboratorry Co, Ltd. 2010-03-11 US disclosed
WO-2010026859-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-03-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100181905-A1 Organometallic Complex, and Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device Using the Organometallic Complex CCNE2, AP2M1, LAGE3 JAK3 2674/4885DYRK1A 4614/4885KMT2A 1737/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.