SCHEMBL4752099

SCHEMBL4752099

Cc1cnc(-c2ccc(F)cc2)c(C)n1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
JAK3 P52333 1/20 0.57
ADORA1 P30542 4/20 0.41
ADORA2A P29274 4/20 0.41
ADORA2B P29275 2/20 0.41
MAPK14 Q16539 5/20 0.41
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HTR2A P28223 1/20 0.38
HTR2C P28335 1/20 0.38
HTR2B P41595 1/20 0.38
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
HSD17B10 Q99714 1/20 0.37
ADORA3 P0DMS8 1/20 0.37
MAPK10 P53779 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1999851 0.86 ADORA1 (0.46) JAK3ADORA1ADORA2AADORA2BMAPK14
SCHEMBL11369579 0.81 ADORA2A (0.56) JAK3ADORA1ADORA2AADORA2BMAPK14
SCHEMBL29476061 0.80 JAK3 (0.56) JAK3ADORA1ADORA2AADORA2BRAB9A
SCHEMBL3335530 0.80 JAK3 (0.56) JAK3ADORA1ADORA2AADORA2BRAB9A
SCHEMBL5010264 0.79 PDGFRB (0.41) JAK3ADORA1ADORA2AADORA2BMAPK14
SCHEMBL29403615 0.78 JAK3 (0.54) JAK3ADORA1ADORA2AADORA2BRAB9A
SCHEMBL31032716 0.78 JAK3 (0.54) JAK3ADORA1ADORA2AADORA2BRAB9A
SCHEMBL27825747 0.78 JAK3 (0.54) JAK3ADORA1ADORA2AADORA2BRAB9A
SCHEMBL28313697 0.78 JAK3 (0.54) JAK3ADORA1ADORA2AADORA2BRAB9A
SCHEMBL3212419 0.78 JAK3 (0.54) JAK3NPC1RAB9AKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9978977-B2 Light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LAB (JP) 2018-05-22 US disclosed
US-9978977-B2 Light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LAB (JP) 2018-05-22 US disclosed
US-20170263878-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-09-14 US disclosed
US-20170263878-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-09-14 US disclosed
US-9666825-B2 Light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-05-30 US disclosed
US-9666825-B2 Light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-05-30 US disclosed
US-20160293877-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-10-06 US disclosed
US-20160293877-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-10-06 US disclosed
US-9379345-B2 Light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-06-28 US disclosed
US-9379345-B2 Light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-06-28 US disclosed
US-20150102331-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2015-04-16 US disclosed
US-20150102331-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2015-04-16 US disclosed
WO-2008149828-A1 ORGANOMETALLIC COMPLEX, AND LIGHT-EMITTING MATERIA LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-12-11 WO disclosed
WO-2008149828-A1 ORGANOMETALLIC COMPLEX, AND LIGHT-EMITTING MATERIA LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-12-11 WO disclosed
US-20080305361-A1 Organometallic Complex, and Light-Emitting Material, Light-Emitting Element, Light-Emitting Device and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-12-11 US disclosed
US-20080305361-A1 Organometallic Complex, and Light-Emitting Material, Light-Emitting Element, Light-Emitting Device and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-12-11 US disclosed
US-20080305361-A1 Organometallic Complex, and Light-Emitting Material, Light-Emitting Element, Light-Emitting Device and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080305361-A1 Organometallic Complex, and Light-Emitting Material, Light-Emitting Element, Light-Emitting Device and Electronic Device CRY1, CCNE2, IK JAK3 2303/4885ADORA1 2881/4885ADORA2A 3533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.