Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | MGLL | Q99685 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1068467 | 0.90 | ALDH1A1 (0.87) | LMNAPOLBALDH1A1MGLLNPSR1 | |
| SCHEMBL1065164 | 0.86 | LMNA (0.93) | LMNAPOLBALDH1A1MGLL | |
| SCHEMBL11371705 | 0.86 | LMNA (0.70) | LMNAPOLBALDH1A1MGLLNPSR1 | |
| SCHEMBL1065271 | 0.85 | LMNA (0.90) | LMNAPOLBALDH1A1MGLL | |
| SCHEMBL27865087 | 0.84 | ALDH1A1 (0.72) | LMNAPOLBALDH1A1MGLLNPSR1 | |
| SCHEMBL10438344 | 0.83 | LMNA (0.76) | LMNAPOLBALDH1A1MGLL | |
| SCHEMBL873613 | 0.83 | LMNA (0.76) | LMNAPOLBALDH1A1MGLL | |
| SCHEMBL20548703 | 0.83 | LMNA (0.76) | LMNAPOLBALDH1A1MGLL | |
| SCHEMBL8425153 | 0.83 | ALDH1A1 (1.00) | LMNAPOLBALDH1A1MGLLNPSR1 | |
| SCHEMBL7602172 | 0.83 | LMNA (0.65) | LMNAPOLBALDH1A1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5186450-A | — | — | None | — | — | JP | disclosed |
| CN-107530260-B | Skin external preparation | 株式会社林原 | 2021-08-27 | — | — | CN | disclosed |
| EP-3398585-B1 | EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME | HAYASHIBARA CO (JP) | 2020-02-26 | — | — | EP | disclosed |
| CN-106413677-B | It is anti-aging to use skin preparations for extenal use | 株式会社林原 | 2019-09-24 | — | — | CN | disclosed |
| US-20190008747-A1 | EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME | Hayashibara Co., Ltd. (JP) | 2019-01-10 | — | — | US | disclosed |
| CN-105585601-B | Anti-aging skin external composition and preparation method thereof | 株式会社林原 | 2018-11-13 | — | — | CN | disclosed |
| EP-3398585-A1 | EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME | Hayashibara Co., Ltd. (JP) | 2018-11-07 | — | — | EP | disclosed |
| US-10111822-B2 | External dermal composition for anti-ageing and method for producing the same | Hayashibara Co., Ltd. (JP) | 2018-10-30 | — | — | US | disclosed |
| EP-2939657-B1 | SKIN-EXTERIOR ANTI-AGEING COMPOSITION AND PRODUCTION METHOD THEREFOR | HAYASHIBARA CO (JP) | 2018-08-08 | — | — | EP | disclosed |
| CN-106413677-A | Anti-aging external skin preparation | 株式会社林原 | 2017-02-15 | — | — | CN | disclosed |
| EP-2939657-A1 | SKIN-EXTERIOR ANTI-AGEING COMPOSITION AND PRODUCTION METHOD THEREFOR | Hayashibara Co., Ltd. (JP) | 2015-11-04 | — | — | EP | disclosed |
| CN-104918603-A | Anti-aging skin external composition and preparation method thereof | HAYASHIBARA CO | 2015-09-16 | — | — | CN | disclosed |
| CN-101212952-B | External preparation for skin | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2012-02-08 | — | — | CN | disclosed |
| US-20100034757-A1 | EXTRACT POWDER OF INDIGO PLANT, AND ITS PREPARATION AND USES | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2010-02-11 | — | — | US | disclosed |
| US-20090263339-A1 | AGENT FOR EXTERNAL APPLICATION TO THE SKIN | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKY (JP) | 2009-10-22 | — | — | US | disclosed |
| CN-101541340-A | Blue grass extract powder, method for producing same, and use of blue grass extract powder | HAYASHIBARA BIOCHEM LAB (JP) | 2009-09-23 | — | — | CN | disclosed |
| EP-2087903-A1 | EXTRACT POWDER OF INDIGO-CONTAINING PLANT, METHOD FOR PRODUCTION THEREOF, AND USE THEREOF | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2009-08-12 | — | — | EP | disclosed |
| CN-101212952-A | External preparation for skin | HAYASHIBARA BIOCHEM LAB (JP) | 2008-07-02 | — | — | CN | disclosed |
| EP-1894558-A1 | AGENT FOR EXTERNAL APPLICATION TO THE SKIN | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2008-03-05 | — | — | EP | disclosed |
| JP-H05186450-A | TETRAHYDROFURFURYL 3-MERCAPTOPROPIONATE AND PERFUME COMPOSITION | T HASEGAWA CO LTD | 1993-07-27 | — | — | JP | disclosed |