Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL321436 | 0.79 | MCHR1 (0.57) | USP30KCNH2MCHR1CHRNA7 | |
| SCHEMBL16422271 | 0.78 | LIPG (0.50) | FFAR4RIPK1EPHX2 | |
| SCHEMBL4186680 | 0.78 | POLB (0.41) | CHRNA7ACACBRIPK1SCDEPHX2 | |
| SCHEMBL17729479 | 0.78 | EPHX2 (0.46) | ACACBRIPK1SCDEPHX2 | |
| SCHEMBL17873485 | 0.77 | ALDH1A1 (0.46) | ACACB | |
| SCHEMBL3414409 | 0.76 | NAAA (0.58) | USP30ACACBRIPK1SCDEPHX2 | |
| SCHEMBL14992804 | 0.74 | EPHX2 (0.46) | USP30RIPK1SCDEPHX2 | |
| SCHEMBL21825158 | 0.74 | HRH3 (0.51) | USP30EPHX2 | |
| SCHEMBL168835 | 0.72 | MCHR1 (0.66) | KCNH2MCHR1 | |
| SCHEMBL1394529 | 0.71 | ACACB (0.38) | KCNH2MCHR1CHRNA7ACACBSCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590969-A2 | THERAPEUTIC AGENTS 976 | AstraZeneca AB (SE) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004588-A2 | THERAPEUTIC AGENTS 976 | ASTRAZENECA AB (SE) | 2012-01-12 | — | — | WO | disclosed |