Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6255974 | 0.93 | TAAR1 (0.55) | OPRK1KDM4ESIGMAR1MEN1KMT2A | |
| SCHEMBL28445715 | 0.90 | SIGMAR1 (0.61) | OPRK1KDM4ESIGMAR1ADRA1AOPRM1 | |
| SCHEMBL3082123 | 0.89 | SIGMAR1 (0.52) | SIGMAR1MEN1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL28452098 | 0.87 | TAAR1 (0.57) | OPRK1KDM4ESIGMAR1ADRA1ASLC6A2 | |
| SCHEMBL21693515 | 0.86 | ESR1 (0.50) | OPRK1KDM4ESIGMAR1SLC6A2LMNA | |
| SCHEMBL11182514 | 0.84 | OPRK1 (0.47) | OPRK1KDM4EMEN1KMT2AADRA1A | |
| SCHEMBL6547008 | 0.84 | ALDH1A1 (0.49) | SIGMAR1MEN1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL11289313 | 0.84 | TP53 (0.52) | SIGMAR1MEN1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL6546874 | 0.84 | ALDH1A1 (0.49) | SIGMAR1MEN1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL19221800 | 0.82 | OPRK1 (0.46) | OPRK1KDM4ESIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105929642-B | Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and method of manufacturing electrophotographic photosensitive member | 佳能株式会社 | 2020-09-01 | — | — | CN | disclosed |
| EP-2088138-B1 | Process for producing isocyanate | ASAHI KASEI CHEMICALS CORP (JP) | 2013-02-27 | — | — | EP | disclosed |
| US-8362293-B2 | Process for producing isocyanates | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2013-01-29 | — | — | US | disclosed |
| US-20100069665-A1 | PROCESS FOR PRODUCING ISOCYANATES | AHAHI KASEI CHEMICALS CORPORATION (JP) | 2010-03-18 | — | — | US | disclosed |
| EP-2088138-A1 | PROCESS FOR PRODUCING ISOCYANATE | Asahi Kasei Chemicals Corporation (JP) | 2009-08-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069665-A1 | PROCESS FOR PRODUCING ISOCYANATES | CPS1, IDH2, PHGDH | OPRK1 4445/4885KDM4E 1511/4885SIGMAR1 2942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.