Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3215545 | 0.81 | MEN1 (0.35) | MAPTNPSR1HTR2AKDM1A | |
| Hydrochloric Acid SCHEMBL3212259 | 0.81 | C5AR1 (0.34) | MAPTNPSR1HTR2AKDM1A | |
| Hydrochloric Acid SCHEMBL3204711 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL3213307 | 0.77 | HTR2A (0.33) | HTR2A | |
| Hydrochloric Acid SCHEMBL3207258 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL3202472 | 0.69 | KDM1A (0.34) | MAPTNPSR1KDM1A | |
| Hydrochloric Acid SCHEMBL3673388 | 0.69 | — | — | |
| SCHEMBL28757848 | 0.68 | ALDH1A1 (0.42) | MAPTNPSR1KDM1A | |
| SCHEMBL6675754 | 0.67 | KDM1A (0.53) | MAPTNPSR1HTR2AKDM1A | |
| SCHEMBL16481156 | 0.67 | KDM1A (0.48) | MAPTNPSR1HTR2AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7671226-B2 | Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-02 | — | — | US | disclosed |
| EP-1426379-B1 | TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME | SUMITOMO CHEMICAL CO (JP) | 2009-11-11 | — | — | EP | disclosed |
| US-7439379-B2 | Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same | SUMITOMO CHEMICAL CO., LTD. (JP) | 2008-10-21 | — | — | US | disclosed |