SCHEMBL6675754

SCHEMBL6675754

c1ccc2c(c1)-c1ccccc1C2c1cccc2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.53
ALDH1A1 P00352 4/20 0.47
HPGD P15428 2/20 0.47
KDM4E B2RXH2 1/20 0.47
TDP2 O95551 1/20 0.47
MAPT P10636 1/20 0.47
ALOX12 P18054 1/20 0.47
MAPK1 P28482 1/20 0.47
CASP3 P42574 1/20 0.47
HTT P42858 1/20 0.47
GALK1 P51570 1/20 0.47
BLM P54132 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
KDM4C Q9H3R0 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
TSHR P16473 2/20 0.44
HSD17B10 Q99714 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16481156 0.91 KDM1A (0.48) KDM1AALDH1A1HPGDKDM4ETDP2
SCHEMBL3224110 0.82 PTPN22 (0.48) KDM1AALDH1A1HPGDKDM4EMAPT
SCHEMBL2358320 0.81 MAPT (0.56) KDM1AALDH1A1HPGDKDM4ETDP2
SCHEMBL29462549 0.81 MAPT (0.56) KDM1AALDH1A1HPGDKDM4ETDP2
SCHEMBL5048011 0.81 ALDH1A1 (0.43) KDM1AALDH1A1HPGDKDM4ETDP2
SCHEMBL5053755 0.79 CYP1A2 (0.46) KDM1AALDH1A1HPGDKDM4EMAPT
SCHEMBL28757848 0.79 ALDH1A1 (0.42) KDM1AALDH1A1HPGDKDM4ETDP2
SCHEMBL3846107 0.78 ERN1 (0.50) KDM1AALDH1A1HPGDKDM4ETDP2
SCHEMBL3200642 0.78 ALDH1A1 (0.42) KDM1AALDH1A1HPGDKDM4ETDP2
SCHEMBL668166 0.77 CYP2C9 (0.49) KDM1AALDH1A1HPGDKDM4ETDP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115636994-B Low-density polyethylene resin composition for film 中国石油天然气股份有限公司 2024-03-01 CN claimed
CN-115636889-B Preparation method of LDPE resin for film product 中国石油天然气股份有限公司 2024-03-01 CN claimed
CN-115636889-A Preparation method of LDPE resin for film product 中国石油天然气股份有限公司 2023-01-24 CN claimed
CN-115636994-A Low-density polyethylene resin composition for film 中国石油天然气股份有限公司 2023-01-24 CN claimed
CN-115636994-B Low-density polyethylene resin composition for film 中国石油天然气股份有限公司 2024-03-01 CN disclosed
CN-115636889-B Preparation method of LDPE resin for film product 中国石油天然气股份有限公司 2024-03-01 CN disclosed
CN-114409493-B Method for synthesizing 9-aryl fluorene compound 浙江工业大学 2024-02-23 CN disclosed
CN-115636889-A Preparation method of LDPE resin for film product 中国石油天然气股份有限公司 2023-01-24 CN disclosed
CN-115636994-A Low-density polyethylene resin composition for film 中国石油天然气股份有限公司 2023-01-24 CN disclosed
CN-114901628-A Fluorene derivative, preparation method and application thereof 大阪燃气化学有限公司 2022-08-12 CN disclosed
CN-114409493-A Method for synthesizing 9-aryl fluorene compound 浙江工业大学 2022-04-29 CN disclosed
US-20040208990-A1 Coating liquid for forming organic LED layer and method of manufacturing organic LED device using it SHARP KABUSHIKI KAISHA (JP) 2004-10-21 US disclosed
EP-0963990-B1 PROCESS FOR PRODUCING CYCLOPENTADIENYL METAL SALTS AND PROCESS FOR PRODUCING CYCLOPENTADIENE DERIVATIVES BY UTILIZING THE SAME SUMITOMO CHEMICAL CO (JP) 2004-10-06 EP disclosed
US-20010003602-A1 Coating liquid for forming organic led layer and method of manufacturing organic led device using it SHARP KABUSHIKI KAISHA (JP) 2001-06-14 US disclosed
US-6197990-B1 REACTING CYCLOPENTADIENE AND METAL HYDRIDE IN PRESENCE OF AMINE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-03-06 US disclosed
EP-0963990-A1 PROCESS FOR PRODUCING CYCLOPENTADIENYL METAL SALTS AND PROCESS FOR PRODUCING CYCLOPENTADIENE DERIVATIVES BY UTILIZING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-12-15 EP disclosed
US-4012336-A ANIONIC POLYMERIZATION CATALYSTS THE GENERAL TIRE & RUBBER COMPANY (US) 1977-03-15 US disclosed
US-3966638-A POLYMERIZATION CATALYST HARGIS IVAN GLEN 1976-06-29 US disclosed
US-3965080-A Polymerization of monomers with alkaline earth metal organometallic compounds THE GENERAL TIRE & RUBBER COMPANY (US) 1976-06-22 US disclosed