SCHEMBL321606

SCHEMBL321606

CCC(CC)(CC)C(O)(O)O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL9098196 0.96 TSHR (0.31) TSHRTDP1
SCHEMBL8079205 0.89 TSHR (0.35) TSHRTDP1
SCHEMBL7629228 0.82 ALDH1A1 (0.31) TSHR
SCHEMBL744729 0.79 FDPS (0.36)
SCHEMBL31053674 0.78
SCHEMBL5032751 0.69 FDPS (0.39)
SCHEMBL10735439 0.69
SCHEMBL220594 0.67
SCHEMBL21183261 0.67
SCHEMBL6650580 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1734 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12172991-B2 Bicycle topoisomerase i inhibiting compounds, process for preparation and use thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2024-12-24 US claimed
EP-4065746-B1 METHOD FOR DEPOSITING A FILM VERSUM MAT US LLC (US) 2024-09-04 EP claimed
EP-3925948-B1 INTERMEDIATE OF ERIBULIN, SYNTHESIS METHOD THEREFOR AND USE THEREOF BEIJING TIENYI LUFU PHARMATECH CO LTD (CN) 2024-08-07 EP claimed
EP-3652158-B1 METHOD FOR PREPARING PYRIMIDONE COMPOUND SUNSHINE LAKE PHARMA CO LTD (CN) 2024-05-29 EP claimed
WO-2024075139-A1 A PROCESS FOR PREPARATION OF FINERENONE AND INTERMEDIATES THEREOF MAITHRI DRUGS PRIVATE LIMITED (IN) 2024-04-11 WO claimed
US-20230058258-A1 METHOD FOR DEPOSITING A FILM VERSUM MATERIALS US, LLC (US) 2023-02-23 US claimed
EP-4065746-A1 METHOD FOR DEPOSITING A FILM Versum Materials US, LLC (US) 2022-10-05 EP claimed
US-11370947-B2 Air conditioning refrigerant oil thermal additive ALLTEMP PRODUCTS COMPANY LIMITED (CA) 2022-06-28 US claimed
US-20210246128-A1 BICYCLE TOPOISOMERASE I INHIBITING COMPOUNDS, PROCESS FOR PREPARATION AND USE THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2021-08-12 US claimed
WO-2021133774-A1 METHOD FOR DEPOSITING A FILM VERSUM MATERIALS US, LLC (US) 2021-07-01 WO claimed
EP-0518428-A2 Process for polymer preparation SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-12-16 EP claimed
EP-0487687-A1 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF TETRAAZAINDENES USEFUL IN PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1992-06-03 EP claimed
WO-1992000291-A1 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF TETRAAZAINDENES USEFUL IN PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1992-01-09 WO claimed
EP-0146935-B1 PROCESSES AND INTERMEDIATES FOR MAKING 16-PHENOXY- AND 16-SUBSTITUTED PHENOXY- PROSTATRIENOIC ACID DERIVATIVES AND THEIR STEREOISOMERS SYNTEX (U.S.A.) INC. (US) 1990-03-14 EP claimed
EP-0256095-A4 ANTI-INFLAMMATORY CARBOXY PREGNANE DERIVATIVES. UNIV FLORIDA AGRICULT MECH (US) 1988-09-28 EP claimed
US-4762919-A STEROIDS FLORIDA AGRICULTURAL AND MECHANICAL UNIVERSITY (US) 1988-08-09 US claimed
EP-0256095-A1 ANTI-INFLAMMATORY CARBOXY PREGNANE DERIVATIVES. UNIV FLORIDA AGRICULT MECH (US) 1988-02-24 EP claimed
WO-1987005028-A1 ANTI-INFLAMMATORY CARBOXY PREGNANE DERIVATIVES FLORIDA AGRICULTURAL AND MECHANICAL UNIVERSITY (US) 1987-08-27 WO claimed
EP-0040958-B1 PROCESS FOR THE SYNTHESIS OF GAMMA-UNSATURATED CARBOXYLIC ACID ESTERS ICI AUSTRALIA LIMITED (AU) 1984-03-14 EP claimed
US-3956349-A TRIETHYL ORTHOACETATE, ACID CATALYST SYNTEX (U.S.A.) INC. (US) 1976-05-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12172991-B2 Bicycle topoisomerase i inhibiting compounds, process for preparation and use thereof TOP1, TOP2A, TOP2B TSHR 3800/4885TDP1 9/4885
US-20210246128-A1 BICYCLE TOPOISOMERASE I INHIBITING COMPOUNDS, PROCESS FOR PREPARATION AND USE THEREOF TOP1, TOP2A, TOP2B TSHR 3800/4885TDP1 9/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.