SCHEMBL3216482

SCHEMBL3216482

CCCCCCCC(=O)Oc1c(O)ccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLM Q9NP87 2/20 0.52
POLK Q9UBT6 2/20 0.52
POLL Q9UGP5 2/20 0.52
POLH Q9Y253 2/20 0.52
MEN1 O00255 5/20 0.44
KMT2A Q03164 5/20 0.44
MAPT P10636 5/20 0.44
ALDH1A1 P00352 2/20 0.44
MAPK1 P28482 2/20 0.44
MCL1 Q07820 2/20 0.44
KDM4E B2RXH2 2/20 0.44
RECQL P46063 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
MAOA P21397 2/20 0.44
CYP3A4 P08684 1/20 0.44
BCL2 P10415 1/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
APEX1 P27695 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5401875 0.84 MAPT (0.57) POLMPOLKPOLLPOLHMEN1
SCHEMBL9115030 0.84 MEN1 (0.50) POLMPOLKPOLLPOLHMEN1
SCHEMBL3954161 0.81 POLM (0.51) POLMPOLKPOLLPOLHMEN1
SCHEMBL27602070 0.81 POLM (0.68) POLMPOLKPOLLPOLHMEN1
SCHEMBL6366589 0.78 POLM (0.71) POLMPOLKPOLLPOLHMEN1
Athraquinones A SCHEMBL5401885 0.78 ALDH1A1 (0.61) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL30317515 0.77 POLM (0.53) POLMPOLKPOLLPOLHMEN1
SCHEMBL28415787 0.77 POLM (0.53) POLMPOLKPOLLPOLHMEN1
SCHEMBL25524551 0.77 POLM (0.53) POLMPOLKPOLLPOLHMEN1
SCHEMBL9177728 0.77 KMT2A (0.58) POLMPOLKPOLLPOLHMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9562899-B2 Method of detecting OXA-048 carbapenemase producing bacteria bioMérieux (FR) 2017-02-07 US disclosed
US-20150160211-A1 METHOD OF DETECTING OXA-048 CARBAPENEMASE PRODUCING BACTERIA BIOMERIEUX (FR) 2015-06-11 US disclosed
CN-104508140-A Method of detecting OXA-048 carbapenemase producing bacteria BIO MERIEUX INC 2015-04-08 CN disclosed
CN-101631874-B Medium for the detection and/or identification of bacteria BIOMERIEUX SA FR 2014-11-12 CN disclosed
US-8216802-B2 Detection medium for gram negative bacteria BIOMERIEUX (FR) 2012-07-10 US disclosed
US-20100062466-A1 MEDIUM FOR THE DETECTION AND/OR IDENTIFICATION OF BACTERIA BIOMERIEUX (FR) 2010-03-11 US disclosed
CN-101631874-A Be used to detect and/or differentiate the medium of bacterium BIOMERIEUX SA 2010-01-20 CN disclosed
EP-2111460-A2 MEDIUM FOR THE DETECTION AND/OR IDENTIFICATION OF BACTERIA BIOMERIEUX (FR) 2009-10-28 EP disclosed
WO-2008104679-A2 MEDIUM FOR THE DETECTION AND/OR IDENTIFICATION OF BACTERIA bioMérieux (FR) 2008-09-04 WO disclosed
US-7217536-B2 Medium and method for detecting/identifying microorganisms BIO MERIEUX (FR) 2007-05-15 US disclosed
EP-1334206-B1 METHOD AND MEDIUM FOR DETECTING/IDENTIFYING MICRO-ORGANISMS WITH ESTERASE AND/OR OSIDASE AND/OR PEPTIDASE AND/OR SULPHATASE AND/OR PHOSPHATASE ACTIVITY BIO MERIEUX (FR) 2006-05-24 EP disclosed
US-20050014215-A1 Method and medium for the detecting/identifying microorganisms with esterase and/or r osidase and/or peptidase and/or sulfatase and/or phosphatase activity BIO MERIEUX (FR) 2005-01-20 US disclosed
EP-1334206-A2 METHOD AND MEDIUM FOR DETECTING/IDENTIFYING MICRO-ORGANISMS WITH ESTERASE AND/OR OSIDASE AND/OR PEPTIDASE AND/OR SULPHATASE AND/OR PHOSPHATASE ACTIVITY BIO MERIEUX (FR) 2003-08-13 EP disclosed
WO-2002040706-A2 METHOD AND MEDIUM FOR DETECTING/IDENTIFYING MICRO-ORGANISMS BIO MERIEUX (FR) 2002-05-23 WO disclosed