SCHEMBL5401875

SCHEMBL5401875

CCCCCCCC(=O)Oc1ccc2c(c1O)C(=O)c1ccccc1C2=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.57
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
NPC1 O15118 2/20 0.57
RAB9A P51151 2/20 0.57
POLM Q9NP87 2/20 0.56
POLK Q9UBT6 2/20 0.56
POLL Q9UGP5 2/20 0.56
POLH Q9Y253 2/20 0.56
ELANE P08246 8/20 0.49
CTSG P08311 4/20 0.47
MITF O75030 1/20 0.47
ALDH1A1 P00352 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
KDM4E B2RXH2 2/20 0.46
RECQL P46063 2/20 0.46
ALOX15 P16050 2/20 0.46
CYP3A4 P08684 1/20 0.46
BCL2 P10415 1/20 0.46
HPGD P15428 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27602070 0.84 POLM (0.68) MAPTMEN1KMT2APOLMPOLK
SCHEMBL3216482 0.84 POLM (0.52) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL3954161 0.82 POLM (0.51) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL26232118 0.82 MAPT (0.42) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL26232114 0.82 MAPT (0.42) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL9115030 0.82 MEN1 (0.50) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL26232106 0.82 MAPT (0.58) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL6366589 0.81 POLM (0.71) MEN1KMT2APOLMPOLKPOLL
SCHEMBL26232112 0.81 MEN1 (0.40) MAPTMEN1KMT2ANPC1RAB9A
Athraquinones A SCHEMBL5401885 0.79 ALDH1A1 (0.61) MAPTMEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7217536-B2 Medium and method for detecting/identifying microorganisms BIO MERIEUX (FR) 2007-05-15 US disclosed
EP-1334206-B1 METHOD AND MEDIUM FOR DETECTING/IDENTIFYING MICRO-ORGANISMS WITH ESTERASE AND/OR OSIDASE AND/OR PEPTIDASE AND/OR SULPHATASE AND/OR PHOSPHATASE ACTIVITY BIO MERIEUX (FR) 2006-05-24 EP disclosed
US-20050014215-A1 Method and medium for the detecting/identifying microorganisms with esterase and/or r osidase and/or peptidase and/or sulfatase and/or phosphatase activity BIO MERIEUX (FR) 2005-01-20 US disclosed
EP-1334206-A2 METHOD AND MEDIUM FOR DETECTING/IDENTIFYING MICRO-ORGANISMS WITH ESTERASE AND/OR OSIDASE AND/OR PEPTIDASE AND/OR SULPHATASE AND/OR PHOSPHATASE ACTIVITY BIO MERIEUX (FR) 2003-08-13 EP disclosed
WO-2002040706-A2 METHOD AND MEDIUM FOR DETECTING/IDENTIFYING MICRO-ORGANISMS BIO MERIEUX (FR) 2002-05-23 WO disclosed