Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLM | Q9NP87 | 2/20 | 0.71 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.71 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.71 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.71 |
| ▸ | ELANE | P08246 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | TTR | P02766 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | CTSG | P08311 | 1/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27602070 | 0.97 | POLM (0.68) | POLMPOLKPOLLPOLHELANE | |
| SCHEMBL6371722 | 0.89 | POLM (0.57) | POLMPOLKPOLLPOLHELANE | |
| SCHEMBL27584372 | 0.87 | ELANE (0.57) | POLMPOLKPOLLPOLHELANE | |
| SCHEMBL6367288 | 0.83 | ELANE (0.55) | POLMPOLKPOLLPOLHELANE | |
| SCHEMBL14315096 | 0.81 | POLM (0.66) | POLMPOLKPOLLPOLHKDM4E | |
| SCHEMBL5401875 | 0.81 | MAPT (0.57) | POLMPOLKPOLLPOLHELANE | |
| SCHEMBL10407328 | 0.81 | KDM4E (0.68) | POLMPOLKPOLLPOLHKDM4E | |
| SCHEMBL27602059 | 0.80 | ELANE (0.56) | POLMPOLKPOLLPOLHELANE | |
| SCHEMBL15549264 | 0.79 | KMT2A (0.66) | POLMPOLKPOLLPOLHKDM4E | |
| SCHEMBL15548290 | 0.79 | KMT2A (0.66) | POLMPOLKPOLLPOLHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009924-A1 | Synthesis and pharmaceuticals of novel bis-substituted anthraquinone derivatives | HUANG HSU-SHAN (TW) | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009924-A1 | Synthesis and pharmaceuticals of novel bis-substituted anthraquinone derivatives | NFE2L2, NR2F2, TFAM | POLM 946/4885POLK 789/4885POLL 3836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.