SCHEMBL321666

SCHEMBL321666

C=C(C)C(=O)OC(C)(C)CN=C=O

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
TSHR P16473 3/20 0.32
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5163549 0.81 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL367296 0.75 TSHR (0.32) ALDH1A1TSHRTHRB
SCHEMBL22353268 0.74 ALDH1A1 (0.44) ALDH1A1TSHRTHRB
SCHEMBL1067047 0.74 ALDH1A1 (0.44) ALDH1A1TSHRTHRB
SCHEMBL1371760 0.72 ALDH1A1 (0.42) ALDH1A1TSHRTHRB
SCHEMBL21496027 0.72 ALDH1A1 (0.42) ALDH1A1TSHRTHRB
SCHEMBL347723 0.72 ALDH1A1 (0.42) ALDH1A1TSHRTHRB
SCHEMBL23633202 0.72 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL17006924 0.72 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL7130273 0.72 ALDH1A1 (0.38) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5075384-A Air-drying, curable protective coatings comprising an allyl alcohol-styrene copolymer carbamylated by an unsaturated isocyanate, an acrylic monomer and an allyl monomer; gloss; toughness MONSANTO (US) 1991-12-24 US claimed
US-5049623-A Solvent resistance, high gloss MONSANTO COMPANY (US) 1991-09-17 US claimed
US-5030696-A Air- or heat-curable protective coatings of unsaturated isocyanate-modified styrene-allyl alcohol copolymer, an acrylic compound and an allyl compound; furniture; toughness MONSANTO COMPANY (US) 1991-07-09 US claimed
US-5010155-A Hydrophilic film CIBA-GEIGY CORPORATION (US) 1991-04-23 US claimed
US-11927512-B2 Method for determining coating thickness on coated contact lenses ALCON INC. (CH) 2024-03-12 US disclosed
EP-2788797-B1 CONTACT LENSES WITH ENZYMATICALLY DEGRADABLE COATINGS THEREON ALCON INC (CH) 2023-06-07 EP disclosed
US-20210131923-A1 METHOD FOR DETERMINING COATING THICKNESS ON COATED CONTACT LENSES ALCON INC. (CH) 2021-05-06 US disclosed
CN-106896422-B Silicone hydrogel lenses with nanotextured surfaces 爱尔康公司 2021-03-23 CN disclosed
US-9950483-B2 Method for determining the surface concentration of carboxyl groups on a lens NOVARTIS AG (CH) 2018-04-24 US disclosed
US-20160097939-A1 SILICONE HYDROGEL LENSES WITH NANO-TEXTURED SURFACES ALCON INC. (CH) 2016-04-07 US disclosed
US-9261626-B2 Contact lenses with enzymatically degradable coatings thereon NOVARTIS AG (CH) 2016-02-16 US disclosed
US-9244195-B2 Silicone hydrogel lenses with nano-textured surfaces NOVARTIS AG (CH) 2016-01-26 US disclosed
EP-0586268-A1 A pathogenic substance removing material and a blood filter comprising said material TERUMO KABUSHIKI KAISHA (JP) 1994-03-09 EP disclosed
US-5102949-A Ethylenically unsaturated carbamates and coating compositions MONSANTO COMPANY (US) 1992-04-07 US disclosed
US-5075384-A Air-drying, curable protective coatings comprising an allyl alcohol-styrene copolymer carbamylated by an unsaturated isocyanate, an acrylic monomer and an allyl monomer; gloss; toughness MONSANTO (US) 1991-12-24 US disclosed
US-5055518-A Ethylenically unsaturated carbamates and coating compositions MONSANTO COMPANY (US) 1991-10-08 US disclosed
US-5049623-A Solvent resistance, high gloss MONSANTO COMPANY (US) 1991-09-17 US disclosed
US-5030696-A Air- or heat-curable protective coatings of unsaturated isocyanate-modified styrene-allyl alcohol copolymer, an acrylic compound and an allyl compound; furniture; toughness MONSANTO COMPANY (US) 1991-07-09 US disclosed
US-5026771-A Coating compositions containing ethylenically unsaturated carbamates MONSANTO COMPANY (US) 1991-06-25 US disclosed
US-5010155-A Hydrophilic film CIBA-GEIGY CORPORATION (US) 1991-04-23 US disclosed