SCHEMBL367296

SCHEMBL367296

C=CC(=O)OC(C)(C)CN=C=O

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.32
ALDH1A1 P00352 4/20 0.32
TP53 P04637 3/20 0.32
HIF1A Q16665 3/20 0.32
CYP3A4 P08684 2/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL27981628 0.94
SCHEMBL29151968 0.81 ALDH1A1 (0.33) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL10628799 0.81 THRB (0.34) TSHRHPGDTHRB
SCHEMBL5163889 0.81 TSHR (0.30) TSHR
SCHEMBL321666 0.75 ALDH1A1 (0.34) TSHRALDH1A1THRB
SCHEMBL4590512 0.74 TSHR (0.40) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL7158382 0.74 TSHR (0.40) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1374290 0.72 ALDH1A1 (0.47) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL302801 0.72 THRB (0.43) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL27814320 0.72 TSHR (0.39) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078209-A1 SILICONE HYDROGEL INK BINDER FOR CONTACT LENSES BAUSCH & LOMB IRELAND LTD (IE) 2026-03-19 US claimed
WO-2015195659-A1 ACRYLATE GEL NAIL COATING COMPOSITIONS ELEMENTIS SPECIALTIES, INC. (US) 2015-12-23 WO claimed
US-20150359724-A1 Acrylate Gel Nail Coating Compositions ELEMENTIS SPECIALTIES, INC. 2015-12-17 US claimed
US-7678870-B2 Processable molecularly imprinted polymers THE JOHNS HOPKINS UNIVERSITY (US) 2010-03-16 US claimed
US-20070197746-A1 Processable molecularly imprinted polymers THE JOHNS HOPKINS UNIVERSITY 2007-08-23 US claimed
EP-1733211-A4 PROCESSABLE MOLECULARLY IMPRINTED POLYMERS UNIV JOHNS HOPKINS (US) 2007-05-30 EP claimed
EP-1733211-A1 PROCESSABLE MOLECULARLY IMPRINTED POLYMERS THE JOHNS-HOPKINS UNIVERSITY (US) 2006-12-20 EP claimed
US-20050276781-A1 Molecularly imprinted phosphate binders for therapeutic use UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2005-12-15 US claimed
WO-2005103655-A1 PROCESSABLE MOLECULARLY IMPRINTED POLYMERS THE JOHNS HOPKINS UNIVERSITY (US) 2005-11-03 WO claimed
EP-0425436-B1 Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof CIBA GEIGY AG (CH) 1996-12-27 EP claimed
EP-0493320-B1 Fluorine and/or Silicone containing poly(alkylene-oxide)-block copolymer hydrogels and contact lenses thereof CIBA GEIGY AG (CH) 1996-07-31 EP claimed
EP-0406161-B1 Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof CIBA GEIGY AG (CH) 1995-02-22 EP claimed
US-5334681-A High oxygen permeability; resiliency, flexibility; wettability; biocompatibility CIBA-GEIGY CORPORATION (US) 1994-08-02 US claimed
EP-0493320-A2 Fluorine and/or Silicone containing poly(alkylene-oxide)-block copolymer hydrogels and contact lenses thereof CIBA-GEIGY AG (CH) 1992-07-01 EP claimed
US-5115056-A FLUORINE AND/OR SILICONE CONTAINING POLY(ALKYLENE-OXIDE)-BLOCK COPOLYMERS AND CONTACT LENSES THEREOF CIBA-GEIGY CORPORATION (US) 1992-05-19 US claimed
EP-0425436-A2 Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof CIBA-GEIGY AG (CH) 1991-05-02 EP claimed
US-5010141-A Heat- or UV-curable acrylic resins; coatings; films; biocompatible, water-swelling, oxygen-permeable contact lenses CIBA-GEIGY CORPORATION (US) 1991-04-23 US claimed
EP-0406161-A2 Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof CIBA-GEIGY AG (CH) 1991-01-02 EP claimed
US-20260078209-A1 SILICONE HYDROGEL INK BINDER FOR CONTACT LENSES BAUSCH & LOMB IRELAND LTD (IE) 2026-03-19 US disclosed
US-4233425-A CURABLE FLOORING MATERIALS THE DOW CHEMICAL COMPANY (US) 1980-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078209-A1 SILICONE HYDROGEL INK BINDER FOR CONTACT LENSES CRYAA, CRYAB, CRYZ TSHR 553/4885ALDH1A1 2751/4885TP53 807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.