SCHEMBL3216898

SCHEMBL3216898

FS(F)(F)N1CCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6259714 0.96 CA1 (0.45)
SCHEMBL31071498 0.72
SCHEMBL107246 0.69 CA1 (0.55)
SCHEMBL12935712 0.69 CA1 (0.55)
SCHEMBL526119 0.69 CA12 (0.52)
SCHEMBL106410 0.69 CA1 (0.55)
SCHEMBL994469 0.65
SCHEMBL2101942 0.62 CA1 (0.55)
SCHEMBL993338 0.62 CA1 (0.55)
SCHEMBL1546827 0.61 POLB (0.87)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100056581-A1 Substituted Piperidino Phenyloxazolidinones PATEL MAHESH VITHALBHAI 2010-03-04 US claimed
US-4284764-A Process for the preparation of 5-fluoro-5-deoxy and 5-epi-fluoro-5-deoxy-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols and novel 5-fluoro-5-deoxy and 5-epi-fluoro-5-deoxy derivatives produced thereby SCHERING CORPORATION (US) 1981-08-18 US claimed
CN-104109077-B A kind of preparation method of 2,3,3,3-tetrafluoeopropene JIANG University OF TECHNOLOGY (CN) 2015-11-25 CN disclosed
EP-2018792-B1 SUBSTITUTED PIPERIDINO PHENYLOXAZOLIDINONES WOCKHARDT LTD (IN) 2015-09-16 EP disclosed
CN-104109077-A A preparing method of 2,3,3,3-tetrafluoropropene UNIV ZHEJIANG TECHNOLOGY 2014-10-22 CN disclosed
US-8217058-B2 Substituted piperidino phenyloxazolidinones WOCKHARDT LTD. (IN) 2012-07-10 US disclosed
US-20100056581-A1 Substituted Piperidino Phenyloxazolidinones PATEL MAHESH VITHALBHAI 2010-03-04 US disclosed
EP-2018792-A2 SUBSTITUTED PIPERIDINO PHENYLOXAZOLIDINONES Wockhardt Limited (IN) 2009-01-28 EP disclosed
WO-2007132314-A2 SUBSTITUTED PIPERIDINO PHENYLOXAZOLIDINONES WOCKHARDT LTD (IN) 2007-11-22 WO disclosed
EP-0009227-B1 FLUORINATION PROCESS AND FLUORO ANALOGS OF HYDROCODONE AND OXYCODONE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-09-01 EP disclosed
US-4284764-A Process for the preparation of 5-fluoro-5-deoxy and 5-epi-fluoro-5-deoxy-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols and novel 5-fluoro-5-deoxy and 5-epi-fluoro-5-deoxy derivatives produced thereby SCHERING CORPORATION (US) 1981-08-18 US disclosed
US-4246270-A TRANQUILIZERS, MUSCLE RELAXANTS, AND SEDATIVES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-01-20 US disclosed
US-4241065-A Fluoro analogs of hydrocodone and oxycodone useful as analgesics, narcotic antagonists or both E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-12-23 US disclosed
US-4236008-A MORPHINE DERIVATIVES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-11-25 US disclosed
EP-0017205-A1 Process for the preparation of N-aryl-oxazolidine-2,4-diones BASF Aktiengesellschaft (DE) 1980-10-15 EP disclosed
US-4212815-A REACTING A KETONE WITH AN N,N-DISUBSTITUTED AMINOSULFUR TRIFLUORIDE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-07-15 US disclosed
EP-0009227-A1 Fluorination process and fluoro analogs of hydrocodone and oxycodone E.I. DU PONT DE NEMOURS AND COMPANY (US) 1980-04-02 EP disclosed
US-4120856-A REACTING 3-HYDROXY-BENZODIAZEPINES WITH AMINOSULFUR TRIFLUORIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-10-17 US disclosed
US-3940402-A POLYMERIZATION CATALYSTS E. I. DUPONT DE NEMOURS AND COMPANY (US) 1976-02-24 US disclosed