Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3216898 | 0.96 | — | — | |
| SCHEMBL12935712 | 0.73 | CA1 (0.55) | CA1CA2POLBTSHRKMT2A | |
| SCHEMBL107246 | 0.73 | CA1 (0.55) | CA1CA2POLBTSHRKMT2A | |
| SCHEMBL106410 | 0.73 | CA1 (0.55) | CA1CA2POLBTSHRKMT2A | |
| SCHEMBL31071498 | 0.69 | — | — | |
| SCHEMBL526119 | 0.67 | CA12 (0.52) | POLBTSHRKMT2AMEN1MGLL | |
| SCHEMBL993338 | 0.67 | CA1 (0.55) | CA1CA2POLBTSHRKMT2A | |
| SCHEMBL2101942 | 0.67 | CA1 (0.55) | CA1CA2POLBTSHRKMT2A | |
| SCHEMBL19413293 | 0.64 | CA1 (0.45) | CA1CA2POLBTSHRKMT2A | |
| SCHEMBL5280013 | 0.64 | POLB (0.93) | CA1CA2POLBTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822909-A | 7-fluoroprostaglandins and process for their production | ASASHI GLASS COMPANY LTD. (JP) | 1989-04-18 | — | — | US | claimed |
| JP-63048278-A | — | — | None | — | — | JP | disclosed |
| CN-104109077-B | A kind of preparation method of 2,3,3,3-tetrafluoeopropene | JIANG University OF TECHNOLOGY (CN) | 2015-11-25 | — | — | CN | disclosed |
| CN-104109077-A | A preparing method of 2,3,3,3-tetrafluoropropene | UNIV ZHEJIANG TECHNOLOGY | 2014-10-22 | — | — | CN | disclosed |
| EP-0930296-B2 | FLUORINATED PROSTAGLANDIN DERIVATIVES AND MEDICINES | ASAHI GLASS CO LTD (JP) | 2005-11-02 | — | — | EP | disclosed |
| CN-1108289-C | Difluoroprostaglundin derivatives and their use | ASAHI GLASS CO LTD (JP) | 2003-05-14 | — | — | CN | disclosed |
| EP-0850926-B1 | Difluoroprostaglandin derivatives and their use | ASAHI GLASS CO LTD (JP) | 2002-10-09 | — | — | EP | disclosed |
| EP-0930296-B1 | FLUORINATED PROSTAGLANDIN DERIVATIVES AND MEDICINES | ASAHI GLASS CO LTD (JP) | 2002-07-24 | — | — | EP | disclosed |
| US-5985920-A | COMPOUNDS FOR TREATMENT OF VISION DEFECTS SUCH AS GLAUCOMA | ASAHI GLASS COMPANY LTD. (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0930296-A1 | FLUORINATED PROSTAGLANDIN DERIVATIVES AND MEDICINES | ASAHI GLASS COMPANY LTD. (JP) | 1999-07-21 | — | — | EP | disclosed |
| US-4552871-A | ALDOSTERONE-ANTAGONISTIC, DIURETICS | CIBA GEIGY CORPORATION (US) | 1985-11-12 | — | — | US | disclosed |
| EP-0148953-A1 | 7-FLUOROPROSTAGLANDINS AND PROCESS FOR THEIR PREPARATION | ASAHI GLASS COMPANY LTD. (JP) | 1985-07-24 | — | — | EP | disclosed |
| EP-0009227-B1 | FLUORINATION PROCESS AND FLUORO ANALOGS OF HYDROCODONE AND OXYCODONE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-09-01 | — | — | EP | disclosed |
| US-4241065-A | Fluoro analogs of hydrocodone and oxycodone useful as analgesics, narcotic antagonists or both | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-12-23 | — | — | US | disclosed |
| US-4236008-A | MORPHINE DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4212815-A | REACTING A KETONE WITH AN N,N-DISUBSTITUTED AMINOSULFUR TRIFLUORIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| EP-0009227-A1 | Fluorination process and fluoro analogs of hydrocodone and oxycodone | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-04-02 | — | — | EP | disclosed |
| US-4172075-A | Fluoro-steroids and processes for their manufacture | CIBA-GEIGY CORPORATION (US) | 1979-10-23 | — | — | US | disclosed |
| US-4092310-A | Difluorosteroids and processes for their manufacture | CIBA-GEIGY CORPORATION (US) | 1978-05-30 | — | — | US | disclosed |
| US-3976691-A | Dialkylaminosulfur trifluorides as fluorinating agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-08-24 | — | — | US | disclosed |