SCHEMBL526119

SCHEMBL526119

FS(F)(F)N1CCOCC1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.52
CA7 P43166 1/20 0.52
CA14 Q9ULX7 1/20 0.52
SMN1; SMN2 Q16637 5/20 0.44
TSHR P16473 4/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
POLB P06746 2/20 0.37
MGLL Q99685 1/20 0.36
LMNA P02545 1/20 0.33
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32
MMP1 P03956 1/20 0.32
MMP3 P08254 1/20 0.32
MMP8 P22894 1/20 0.32
CYP2A13 Q16696 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20470599 0.97 CA12 (0.50) CA12CA7CA14SMN1; SMN2TSHR
SCHEMBL27652381 0.92 CA12 (0.46) CA12CA7CA14SMN1; SMN2TSHR
SCHEMBL26560789 0.79 CA12 (0.50) CA12CA7CA14SMN1; SMN2TSHR
SCHEMBL108245 0.77 CA12 (0.62) CA12CA7CA14SMN1; SMN2TSHR
SCHEMBL4442972 0.73 CA12 (0.44) CA12CA7CA14SMN1; SMN2TSHR
SCHEMBL995945 0.71 CA12 (0.62) CA12CA7CA14SMN1; SMN2TSHR
SCHEMBL19413262 0.69 CA12 (0.52) CA12CA7CA14SMN1; SMN2TSHR
SCHEMBL19413304 0.69 CA12 (0.52) CA12CA7CA14SMN1; SMN2TSHR
SCHEMBL4724826 0.69 CA12 (1.00) CA12CA7CA14SMN1; SMN2TSHR
SCHEMBL18963225 0.69 CA12 (0.52) CA12CA7CA14SMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 381 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245089-A1 PROCESSES FOR PREPARING TETRALIN COMPOUNDS ARCUS BIOSCIENCES, INC. (US) 2025-11-27 WO claimed
EP-4200309-A1 STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES ATEA Pharmaceuticals, Inc. (US) 2023-06-28 EP claimed
CN-115884977-A Stereoselective preparation of selected purine phosphoramidates 阿堤亚制药公司 2023-03-31 CN claimed
CN-109803952-B Sulfamic acid derivatives and process for preparing same 魁北克电力公司 2022-10-04 CN claimed
CN-112279785-B 3, 3-difluorocyclobutylamine hydrochloride intermediate and synthetic method thereof, and 3, 3-difluorocyclobutylamine hydrochloride synthetic method 苏利制药科技江阴有限公司 2022-08-16 CN claimed
CN-114671848-A Synthetic method of aromatic fused oxygen sulfur heterocyclic compound 郑州药领医药科技有限公司 2022-06-28 CN claimed
US-11345657-B2 Sulfamic acid derivatives and processes for their preparation HYDRO-QUEBEC (CA) 2022-05-31 US claimed
WO-2022040473-A1 STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES Atea Pharmaceuticals, Inc. (US) 2022-02-24 WO claimed
CN-100543032-C Streptogramin derivatives, preparation method and compositions containing them AVETIS PHARMA S A (FR) 2009-09-23 CN claimed
EP-1723091-B1 SYNTHESIS OF CARBON-LABELED PERFLUOROALKYL COMPOUNDS DU PONT (US) 2008-11-05 EP claimed
CN-101233098-A Process for the preparation of geminal ((difluorocycloalkyl) methyl) amines ASTRAZENECA AB (SE) 2008-07-30 CN claimed
US-20080167488-A1 Process for the Preparation of Geminal ((Difluorocycloalkyl)Methyl) Amines ASTRAZENECA AB (SE) 2008-07-10 US claimed
EP-1912930-A1 PROCESS FOR THE PREPARATION OF GEMINAL ((DIFLUOROCYCLOALKYL)METHYL) AMINES. AstraZeneca AB (SE) 2008-04-23 EP claimed
US-7351870-B2 Synthesis of carbon-labeled perfluoroalkyl compounds E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-04-01 US claimed
WO-2007013848-A1 PROCESS FOR THE PREPARATION OF GEMINAL ((DIFLUOROCYCLOALKYL)METHYL) AMINES. ASTRAZENECA AB (SE) 2007-02-01 WO claimed
EP-1723091-A2 SYNTHESIS OF CARBON-LABELED PERFLUOROALKYL COMPOUNDS E.I.Du pont de nemours and company (US) 2006-11-22 EP claimed
WO-2005092820-A2 SYNTHESIS OF CARBON-LABELED PERFLUOROALKYL COMPOUNDS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-10-06 WO claimed
US-20050197510-A1 Synthesis of carbon-labeled perfluoroalkyl compounds THE CHEMOURS COMPANY FC, LLC 2005-09-08 US claimed
CN-1358194-A Streptogramin derivatives, preparation method and compositions containing them AVETIS PHARMA S A (FR) 2002-07-10 CN claimed
CN-1137797-A Rapamycin derivatives useful as immunosuppressants SANDOZ LTD (CH) 1996-12-11 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080167488-A1 Process for the Preparation of Geminal ((Difluorocycloalkyl)Methyl) Amines GMNN, GNMT, DNMT1 CA12 3328/4885CA7 4001/4885CA14 3827/4885
US-11345657-B2 Sulfamic acid derivatives and processes for their preparation STS, SCLY, MPST CA12 57/4885CA7 76/4885CA14 59/4885
US-20050197510-A1 Synthesis of carbon-labeled perfluoroalkyl compounds ZYX, CYP2F1, AFF1 CA12 1243/4885CA7 900/4885CA14 1109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.