Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | PAM | P19021 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3216997 | 0.93 | TSHR (0.51) | TSHRMAPTALDH1A1GAALMNA | |
| SCHEMBL481761 | 0.82 | TSHR (0.45) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL87404 | 0.81 | TSHR (0.67) | TSHRMAPTABCC4ALDH1A1GAA | |
| SCHEMBL2249400 | 0.79 | TSHR (0.70) | TSHRMAPTABCC4ALDH1A1GAA | |
| SCHEMBL14533033 | 0.79 | TSHR (0.70) | TSHRMAPTABCC4ALDH1A1GAA | |
| SCHEMBL530482 | 0.79 | TSHR (0.70) | TSHRMAPTABCC4ALDH1A1GAA | |
| Ethylene SCHEMBL28109697 | 0.79 | TSHR (0.65) | TSHRMAPTABCC4ALDH1A1GAA | |
| SCHEMBL9011445 | 0.79 | TSHR (0.70) | TSHRMAPTABCC4ALDH1A1GAA | |
| SCHEMBL11763281 | 0.79 | TSHR (0.70) | TSHRMAPTABCC4ALDH1A1GAA | |
| SCHEMBL7161127 | 0.77 | TSHR (0.39) | TSHRMAPTABCC4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198473-B2 | Process for preparing organically modified siloxanes | EVONIK GOLDSCHMIDT GMBH (DE) | 2012-06-12 | — | — | US | disclosed |
| US-20100056818-A1 | PROCESS FOR PREPARING ORGANICALLY MODIFIED SILOXANES | EVONIK GOLDSCHMIDT GMBH (DE) | 2010-03-04 | — | — | US | disclosed |
| US-7635581-B2 | Process for preparing organically modified siloxanes | GOLDSCHMIDT GMBH (DE) | 2009-12-22 | — | — | US | disclosed |
| US-20070184006-A1 | PROCESS FOR PREPARING ORGANICALLY MODIFIED SILOXANES | GOLDSCHMIDT GMBH (DE) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070184006-A1 | PROCESS FOR PREPARING ORGANICALLY MODIFIED SILOXANES | HSD17B12, CYP51A1, ESD | TSHR 4695/4885MAPT 4676/4885ABCC4 3885/4885 |
| US-20100056818-A1 | PROCESS FOR PREPARING ORGANICALLY MODIFIED SILOXANES | HSD17B12, CYP51A1, ESD | TSHR 4695/4885MAPT 4676/4885ABCC4 3885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.