SCHEMBL321754

SCHEMBL321754

C=C[N+]1(C(=C)C(=O)OC2CC(=O)NC2=O)CCOCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL321074 0.74
SCHEMBL2128127 0.70 CRBN (0.35)
SCHEMBL309593 0.69 MAP3K14 (0.35)
SCHEMBL7255757 0.69
SCHEMBL3949247 0.68 MAP3K14 (0.40)
SCHEMBL11194050 0.65 MAP3K14 (0.32)
SCHEMBL26689388 0.65 ALDH1A1 (0.33)
SCHEMBL18015890 0.65 MAP3K14 (0.38)
SCHEMBL7264550 0.65 MAP3K14 (0.40)
Acrylamide SCHEMBL7515363 0.64 ALDH1A1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7060804-B2 Method for isolating proteins or protein and nucleic acid associations, or particle and protein complexes, reagent and uses BIOMERIEUX (FR) 2006-06-13 US claimed
US-20060105326-A1 Method for isolating proteins or protein and nucleic acid associations, or particle and protein complexes, reagent and uses BIOMERIEUX (FR) 2006-05-18 US claimed
EP-1248679-B1 METHOD FOR ISOLATING PROTEINS OR PROTEIN AND NUCLEIC ACID ASSOCIATIONS, OR PARTICLE AND PROTEIN COMPLEXES, REAGENT AND USES BIO MERIEUX (FR) 2005-03-09 EP claimed
US-20030175691-A1 Method for isolating proteins or protein and nucleic acid associations, or particle and protein complexes, reagent and uses BIO MERIEUX (FR) 2003-09-18 US claimed
WO-2001052979-A1 METHOD FOR PREPARING STABLE AND FUNCTIONALISED COLLOIDAL PARTICLES AND RESULTING PARTICULATE REAGENT BIO MERIEUX (FR) 2001-07-26 WO claimed
US-8093026-B2 Method for transporting or storing a protein, a virus, a prokaryotic cell, or an eukaryotic cell BIOMERIEUX (FR) 2012-01-10 US disclosed
US-20100209987-A1 Method for isolating proteins or protein and nucleic acid associations, or particle and protein complexes, reagent and uses BIOMERIEUX (FR) 2010-08-19 US disclosed
US-7700744-B2 Method for isolating proteins or protein and nucleic acid associations, or particle and protein complexes, reagent and uses BIOMERIEUX (FR) 2010-04-20 US disclosed
US-7060804-B2 Method for isolating proteins or protein and nucleic acid associations, or particle and protein complexes, reagent and uses BIOMERIEUX (FR) 2006-06-13 US disclosed
US-20060105326-A1 Method for isolating proteins or protein and nucleic acid associations, or particle and protein complexes, reagent and uses BIOMERIEUX (FR) 2006-05-18 US disclosed
US-6909001-B2 Method of making tricyclic aminocyanopyridine compounds PHARMACIA CORPORATION (US) 2005-06-21 US disclosed
EP-1248679-B1 METHOD FOR ISOLATING PROTEINS OR PROTEIN AND NUCLEIC ACID ASSOCIATIONS, OR PARTICLE AND PROTEIN COMPLEXES, REAGENT AND USES BIO MERIEUX (FR) 2005-03-09 EP disclosed
US-20030175691-A1 Method for isolating proteins or protein and nucleic acid associations, or particle and protein complexes, reagent and uses BIO MERIEUX (FR) 2003-09-18 US disclosed
WO-2001052979-A1 METHOD FOR PREPARING STABLE AND FUNCTIONALISED COLLOIDAL PARTICLES AND RESULTING PARTICULATE REAGENT BIO MERIEUX (FR) 2001-07-26 WO disclosed