SCHEMBL321074

SCHEMBL321074

C=C[N+]1(C(=C)C(=O)OC2CC(=O)NC2=O)CCCC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL321754 0.74
SCHEMBL2128127 0.70 CRBN (0.35)
SCHEMBL309593 0.68 MAP3K14 (0.35)
SCHEMBL7255757 0.68
SCHEMBL3949247 0.67 MAP3K14 (0.40)
SCHEMBL7763966 0.66 LMNA (0.36)
SCHEMBL11194050 0.65 MAP3K14 (0.32)
SCHEMBL26689388 0.65 ALDH1A1 (0.33)
SCHEMBL18015890 0.64 MAP3K14 (0.38)
SCHEMBL7264550 0.64 MAP3K14 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7060804-B2 Method for isolating proteins or protein and nucleic acid associations, or particle and protein complexes, reagent and uses BIOMERIEUX (FR) 2006-06-13 US claimed
US-20060105326-A1 Method for isolating proteins or protein and nucleic acid associations, or particle and protein complexes, reagent and uses BIOMERIEUX (FR) 2006-05-18 US claimed
EP-1248679-B1 METHOD FOR ISOLATING PROTEINS OR PROTEIN AND NUCLEIC ACID ASSOCIATIONS, OR PARTICLE AND PROTEIN COMPLEXES, REAGENT AND USES BIO MERIEUX (FR) 2005-03-09 EP claimed
US-20030175691-A1 Method for isolating proteins or protein and nucleic acid associations, or particle and protein complexes, reagent and uses BIO MERIEUX (FR) 2003-09-18 US claimed
US-20020155496-A1 Saturated and unsaturated abietane derivatives, derived conjugates and uses in a diagnostic composition, a reagent and a device BIO MERIEUX (FR) 2002-10-24 US claimed
EP-1248679-A2 METHOD FOR ISOLATING PROTEINS OR PROTEIN AND NUCLEIC ACID ASSOCIATIONS, OR PARTICLE AND PROTEIN COMPLEXES, REAGENT AND USES BIO MERIEUX (FR) 2002-10-16 EP claimed
WO-2001052979-A1 METHOD FOR PREPARING STABLE AND FUNCTIONALISED COLLOIDAL PARTICLES AND RESULTING PARTICULATE REAGENT BIO MERIEUX (FR) 2001-07-26 WO claimed
WO-2001052612-A2 METHOD FOR ISOLATING PROTEINS OR PROTEIN AND NUCLEIC ACID ASSOCIATIONS, AND RESULTING COMPLEXES OF PARTICLES AND PROTEINS BIO MERIEUX (FR) 2001-07-26 WO claimed
US-8093026-B2 Method for transporting or storing a protein, a virus, a prokaryotic cell, or an eukaryotic cell BIOMERIEUX (FR) 2012-01-10 US disclosed
US-20100209987-A1 Method for isolating proteins or protein and nucleic acid associations, or particle and protein complexes, reagent and uses BIOMERIEUX (FR) 2010-08-19 US disclosed
US-7700744-B2 Method for isolating proteins or protein and nucleic acid associations, or particle and protein complexes, reagent and uses BIOMERIEUX (FR) 2010-04-20 US disclosed
US-7060804-B2 Method for isolating proteins or protein and nucleic acid associations, or particle and protein complexes, reagent and uses BIOMERIEUX (FR) 2006-06-13 US disclosed
US-20060105326-A1 Method for isolating proteins or protein and nucleic acid associations, or particle and protein complexes, reagent and uses BIOMERIEUX (FR) 2006-05-18 US disclosed
EP-1248679-B1 METHOD FOR ISOLATING PROTEINS OR PROTEIN AND NUCLEIC ACID ASSOCIATIONS, OR PARTICLE AND PROTEIN COMPLEXES, REAGENT AND USES BIO MERIEUX (FR) 2005-03-09 EP disclosed
US-20030175691-A1 Method for isolating proteins or protein and nucleic acid associations, or particle and protein complexes, reagent and uses BIO MERIEUX (FR) 2003-09-18 US disclosed
US-20020155496-A1 Saturated and unsaturated abietane derivatives, derived conjugates and uses in a diagnostic composition, a reagent and a device BIO MERIEUX (FR) 2002-10-24 US disclosed
EP-1248679-A2 METHOD FOR ISOLATING PROTEINS OR PROTEIN AND NUCLEIC ACID ASSOCIATIONS, OR PARTICLE AND PROTEIN COMPLEXES, REAGENT AND USES BIO MERIEUX (FR) 2002-10-16 EP disclosed
WO-2001052612-A2 METHOD FOR ISOLATING PROTEINS OR PROTEIN AND NUCLEIC ACID ASSOCIATIONS, AND RESULTING COMPLEXES OF PARTICLES AND PROTEINS BIO MERIEUX (FR) 2001-07-26 WO disclosed