SCHEMBL3217541

SCHEMBL3217541

Cc1ccc(CC(C)([Po])c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 6/20 0.44
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
SLC6A2 P23975 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
LMNA P02545 4/20 0.39
POLB P06746 2/20 0.39
CYP2D6 P10635 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
HRH1 P35367 1/20 0.38
ALDH1A1 P00352 1/20 0.38
XBP1 P17861 1/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1853310 0.85 MEN1 (0.36) KIF11MEN1KMT2ASLC6A2TAAR1
SCHEMBL8853831 0.77 KIF11 (0.44) KIF11MEN1KMT2ASLC6A2TAAR1
SCHEMBL2008110 0.77 KIF11 (0.44) KIF11MEN1KMT2ASLC6A2TAAR1
SCHEMBL6682555 0.76 KIF11 (0.50) KIF11MEN1KMT2ASLC6A2TAAR1
SCHEMBL29271946 0.74 KIF11 (0.45) KIF11MEN1KMT2ACYP1A2CYP2C9
SCHEMBL28274128 0.74 KIF11 (0.45) KIF11MEN1KMT2ACYP1A2CYP2C9
SCHEMBL27590092 0.72 KIF11 (0.46) KIF11MEN1KMT2ASLC6A2TAAR1
SCHEMBL10360564 0.72 KIF11 (0.43) KIF11MEN1KMT2ACYP1A2CYP2C9
SCHEMBL18925248 0.72 CYP2C19 (0.43) KIF11MEN1KMT2ASLC6A2TAAR1
SCHEMBL3482019 0.70 KIF11 (0.42) KIF11MEN1KMT2ACYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9499578-B2 Massively parallel synthesis of biopolymeric arrays INTEL CORPORATION (US) 2016-11-22 US disclosed
US-20100035771-A1 Molecular microarrays and helical peptides CABEZAS EDELMIRA 2010-02-11 US disclosed
US-7622295-B2 Molecular microarrays and helical peptides INTEL CORPORATION 2009-11-24 US disclosed
US-20090258796-A1 MASSIVELY PARALLEL SYNTHESIS OF BIOPOLYMERIC ARRAYS RAJASEKARAN JOHN J 2009-10-15 US disclosed
US-20080318808-A1 MASSIVELY PARALLEL SYNTHESIS OF BIOPOLYMERIC ARRAYS RAJASEKARAN JOHN J 2008-12-25 US disclosed
EP-1966230-A1 MASSIVELY PARALLEL SYNTHESIS OF BIOPOLYMERIC ARRAYS Intel Corporation (US) 2008-09-10 EP disclosed
WO-2008097370-A2 METHOD FOR HIGH THROUGHPUT, HIGH VOLUME MANUFACTURING OF BIOMOLECULE MICRO ARRAYS INTEL CORPORATION (US) 2008-08-14 WO disclosed
US-20080145862-A1 Molecular microarrays and helical peptides INTEL CORPORATION 2008-06-19 US disclosed
WO-2007078868-A1 MASSIVELY PARALLEL SYNTHESIS OF BIOPOLYMERIC ARRAYS INTEL CORPORATION (US) 2007-07-12 WO disclosed
US-20070154946-A1 Massively parallel synthesis of biopolymeric arrays INTEL CORPORATION 2007-07-05 US disclosed
US-20070122842-A1 Massively parallel synthesis of proteinaceous biomolecules INTEL CORPORATION 2007-05-31 US disclosed
US-20070122841-A1 Massively parallel synthesis of proteinaceous biomolecules INTEL CORPORATION 2007-05-31 US disclosed