Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.43 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.43 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrogen SCHEMBL9592328 | 0.94 | AHR (0.48) | AHRTSHRRAPGEF4TDP1CYP3A4 | |
| SCHEMBL3786224 | 0.94 | RAPGEF4 (0.47) | AHRTSHRRAPGEF4TDP1CYP3A4 | |
| Nitrogen SCHEMBL28987389 | 0.92 | AHR (0.47) | AHRTSHRRAPGEF4TDP1CYP3A4 | |
| SCHEMBL6865601 | 0.87 | AHR (0.48) | AHRTSHRRAPGEF4TDP1CYP3A4 | |
| SCHEMBL7934061 | 0.84 | RAPGEF4 (0.42) | AHRTSHRRAPGEF4TDP1CYP3A4 | |
| SCHEMBL6800526 | 0.82 | RAPGEF4 (0.41) | AHRTSHRRAPGEF4TDP1CYP3A4 | |
| SCHEMBL902818 | 0.82 | RAPGEF4 (0.58) | AHRTSHRRAPGEF4TDP1CYP3A4 | |
| SCHEMBL979567 | 0.82 | RAPGEF4 (0.41) | AHRTSHRRAPGEF4TDP1CYP3A4 | |
| SCHEMBL1012745 | 0.82 | CYP3A4 (0.55) | AHRTSHRRAPGEF4TDP1CYP3A4 | |
| SCHEMBL15943174 | 0.82 | RAPGEF4 (0.41) | AHRTSHRRAPGEF4TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112110790-B | Preparation method of 3, 5-dihalide benzotrifluoride and 3 '-chloro-5' -trifluoromethyl phenyl trifluoro-ethanone | 台州臻挚生物科技有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-116008331-A | Method for measuring content of liquid electrolyte component of battery | 清华大学 | 2023-04-25 | — | — | CN | claimed |
| CN-102442960-B | Cyanuric chloride derivative as well as preparation method and application thereof | WUHAN INST TECHNOLOGY | 2014-12-24 | — | — | CN | claimed |
| EP-0912492-B1 | METHOD FOR PREPARING HALOGENATED 2-AMINO OR 2-ACETAMIDO TRIFLUOROMETHYLBENZENE DERIVATIVES | RHODIA CHIMIE SA (FR) | 2002-09-25 | — | — | EP | claimed |
| US-6191309-B1 | USING A COMPOUND OF FORMULA X2 IN A SOLVENT SELECTED FROM AN ANHYDROUS HALOGENATED HYDROCARBON, A MIXTURE OF WATER AND A HALOGENATED HYDROCARBON AND OPTIONALLY THE COMPOUND ITSELF, TO GIVE HALOGENATED 2-AMINO OR 2-ACETAMIDOTRIFLUOROMETHYLBENZENE | RHODIA CHIMIE (FR) | 2001-02-20 | — | — | US | claimed |
| EP-0912492-A1 | METHOD FOR PREPARING HALOGENATED 2-AMINO OR 2-ACETAMIDO TRIFLUOROMETHYLBENZENE DERIVATIVES | RHODIA CHIMIE (FR) | 1999-05-06 | — | — | EP | claimed |
| WO-1998002409-A1 | METHOD FOR PREPARING HALOGENATED 2-AMINO OR 2-ACETAMIDO TRIFLUOROMETHYLBENZENE DERIVATIVES | RHODIA CHIMIE (FR) | 1998-01-22 | — | — | WO | claimed |
| CN-117964491-A | Preparation method of 4-trifluoromethyl aniline | 上海立科化学科技有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-113636919-B | Method for synthesizing 3-chloro-5-trifluoromethyl trifluoroacetophenone | 上海恩氟佳科技有限公司 | 2023-10-24 | — | — | CN | disclosed |
| WO-2023134629-A1 | NUCLEAR TRANSPORT REGULATOR AND USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-20 | — | — | WO | disclosed |
| WO-2023134629-A1 | NUCLEAR TRANSPORT REGULATOR AND USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-20 | — | — | WO | disclosed |
| CN-112110790-B | Preparation method of 3, 5-dihalide benzotrifluoride and 3 '-chloro-5' -trifluoromethyl phenyl trifluoro-ethanone | 台州臻挚生物科技有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116008331-A | Method for measuring content of liquid electrolyte component of battery | 清华大学 | 2023-04-25 | — | — | CN | disclosed |
| EP-0912492-A1 | METHOD FOR PREPARING HALOGENATED 2-AMINO OR 2-ACETAMIDO TRIFLUOROMETHYLBENZENE DERIVATIVES | RHODIA CHIMIE (FR) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998002409-A1 | METHOD FOR PREPARING HALOGENATED 2-AMINO OR 2-ACETAMIDO TRIFLUOROMETHYLBENZENE DERIVATIVES | RHODIA CHIMIE (FR) | 1998-01-22 | — | — | WO | disclosed |
| EP-0097357-B1 | PROCESS FOR PREPARING TRIFLUOROMETHYLBENZENE DERIVATIVES | Daikin Kogyo Co., Ltd. (JP) | 1986-01-08 | — | — | EP | disclosed |
| US-4493800-A | REACTING A TRIFLUOROMETHYLHALOGENOBENZENE WITH COPPER CYANIDE | DAIKIN KOGYO CO., LTD. (JP) | 1985-01-15 | — | — | US | disclosed |
| EP-0097357-A1 | Process for preparing trifluoromethylbenzene derivatives | Daikin Kogyo Co., Ltd. (JP) | 1984-01-04 | — | — | EP | disclosed |
| EP-0029123-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED ANILINES, AND SUBSTITUTED ANILINES | BASF Aktiengesellschaft (DE) | 1983-06-08 | — | — | EP | disclosed |
| EP-0029123-A1 | Process for the preparation of substituted anilines, and substituted anilines | BASF Aktiengesellschaft (DE) | 1981-05-27 | — | — | EP | disclosed |