Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.43 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.43 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL321756 | 0.94 | AHR (0.52) | RAPGEF4AHRCES2TSHRALDH1A1 | |
| Nitrogen SCHEMBL9592328 | 0.88 | AHR (0.48) | RAPGEF4AHRCES2TSHRALDH1A1 | |
| SCHEMBL16703924 | 0.87 | RAPGEF4 (0.41) | RAPGEF4AHRCES2TSHRALDH1A1 | |
| SCHEMBL13249067 | 0.87 | RAPGEF4 (0.44) | RAPGEF4AHRCES2TSHRALDH1A1 | |
| Nitrogen SCHEMBL28987389 | 0.86 | AHR (0.47) | RAPGEF4AHRCES2TSHRALDH1A1 | |
| SCHEMBL23045002 | 0.84 | NOTUM (0.46) | RAPGEF4AHRCES2TSHRALDH1A1 | |
| SCHEMBL7934061 | 0.84 | RAPGEF4 (0.42) | RAPGEF4AHRCES2TSHRALDH1A1 | |
| SCHEMBL440959 | 0.83 | CES2 (0.58) | RAPGEF4CES2TSHRALDH1A1CYP3A4 | |
| SCHEMBL15943174 | 0.82 | RAPGEF4 (0.41) | RAPGEF4AHRCES2TSHRALDH1A1 | |
| SCHEMBL6865601 | 0.82 | AHR (0.48) | RAPGEF4AHRCES2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116730879-B | Method for selectively synthesizing 4-amino-N- (hetero) aryl sulfonamide compound | SHAANXI NORMAL UNIVERSITY (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-117185990-B | Compound and organic electroluminescent device comprising same | 烟台丰蓬液晶材料有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-117185990-A | Compound and organic electroluminescent device comprising same | 烟台丰蓬液晶材料有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-116730879-A | Method for selectively synthesizing 4-amino-N- (hetero) aryl sulfonamide compound | 陕西师范大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-110730767-B | Process for producing cycloalkyl (trifluoromethyl) benzene | 东丽精细化工株式会社 | 2022-06-24 | — | — | CN | disclosed |
| US-11066422-B2 | Method of producing cycloalkyl(trifluoromethyl)benzene | TORAY FINE CHEMICALS CO., LTD. (JP) | 2021-07-20 | — | — | US | disclosed |
| US-20210053992-A1 | METHOD OF PRODUCING CYCLOALKYL(TRIFLUOROMETHYL)BENZENE | TORAY FINE CHEMICALS CO., LTD. (JP) | 2021-02-25 | — | — | US | disclosed |
| US-10899687-B2 | Process for the preparation of organic halides | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2021-01-26 | — | — | US | disclosed |
| EP-3653594-A1 | PRODUCTION METHOD FOR CYCLOALKYL(TRIFLUOROMETHYL)BENZENE | Toray Fine Chemicals Co., Ltd. (JP) | 2020-05-20 | — | — | EP | disclosed |
| US-20180282247-A1 | PROCESS FOR THE PREPARATION OF ORGANIC HALIDES | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2018-10-04 | — | — | US | disclosed |
| EP-0968177-B1 | METHOD FOR PRODUCING AROMATIC NITRILES | BAYER AG (DE) | 2002-01-23 | — | — | EP | disclosed |
| US-6268527-B1 | REACTING TRIFLUOROMETHYL SUBSTITUTED AROMATIC COMPOUND WITH CARBON MONOXIDE AND HYDROXY COMPOUND IN PRESENCE OF METAL COMPOUND AND PHOSPHINE DERIVATIVE TO PRODUCE TRIFLUOROMETHYL SUBSTITUTED BENZOIC ACID DERIVATIVE | CENTRAL GLASS COMPANY, LIMITED (JP) | 2001-07-31 | — | — | US | disclosed |
| US-6162942-A | Method for producing aromatic nitriles | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-19 | — | — | US | disclosed |
| JP-2000264853-A | PRODUCTION OF NUCLEUS-CHLORINATED BIS(TRIHALOMETHYL) BENZENE | ASAHI GLASS CO LTD | 2000-09-26 | — | — | JP | disclosed |
| EP-0968177-A1 | METHOD FOR PRODUCING AROMATIC NITRILES | Bayer Aktiengesellschaft (DE) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998037058-A1 | METHOD FOR PRODUCING AROMATIC NITRILES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-08-27 | — | — | WO | disclosed |
| EP-0384392-A1 | Cyanation of haloaromatics utilizing catalysts generated in situ starting with NiCl2 or NiCl2 6H2O | OCCIDENTAL CHEMICAL CORPORATION (US) | 1990-08-29 | — | — | EP | disclosed |
| US-4351975-A | Process for preparing chlorinated compounds | CIBA-GEIGY AG (CH) | 1982-09-28 | — | — | US | disclosed |
| EP-0036840-A2 | Process for the production of chlorinated compounds | CIBA-GEIGY AG (CH) | 1981-09-30 | — | — | EP | disclosed |
| US-4079090-A | Preparation of trichloromethyl-trifluoro methyl-benzenes | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11066422-B2 | Method of producing cycloalkyl(trifluoromethyl)benzene | HCN4, MAP2K4, GRHPR | RAPGEF4 3107/4885AHR 64/4885CES2 3206/4885 |
| US-10899687-B2 | Process for the preparation of organic halides | HDHD5, CBR3, RCC2 | RAPGEF4 3498/4885AHR 1828/4885CES2 188/4885 |
| US-20180282247-A1 | PROCESS FOR THE PREPARATION OF ORGANIC HALIDES | HDHD5, CBR3, RCC2 | RAPGEF4 3498/4885AHR 1828/4885CES2 188/4885 |
| US-20210053992-A1 | METHOD OF PRODUCING CYCLOALKYL(TRIFLUOROMETHYL)BENZENE | HCN4, MAP2K4, GRHPR | RAPGEF4 3107/4885AHR 64/4885CES2 3206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.