Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31329750 | 1.00 | RAPGEF4 (0.41) | RAPGEF4HCAR1AHRPTGS1SLC13A3 | |
| SCHEMBL21945005 | 0.83 | RXRA (0.42) | KIF11CES2P2RX1NOTUMP2RX4 | |
| SCHEMBL321756 | 0.82 | AHR (0.52) | RAPGEF4AHRSLC13A3CES2NOTUM | |
| SCHEMBL186842 | 0.82 | GABRA1 (0.52) | PTGS1KIF11CES2P2RX1GABRA1 | |
| SCHEMBL3786224 | 0.82 | RAPGEF4 (0.47) | RAPGEF4AHRSLC13A3CES2P2RX1 | |
| SCHEMBL69029 | 0.82 | PTGS1 (0.52) | PTGS1KIF11CES2P2RX1GABRA1 | |
| SCHEMBL29384937 | 0.79 | GABRA1 (0.50) | PTGS1KIF11CES2P2RX1GABRA1 | |
| Water SCHEMBL21493255 | 0.79 | GABRA1 (0.50) | PTGS1KIF11CES2P2RX1GABRA1 | |
| SCHEMBL29005991 | 0.79 | GABRA1 (0.50) | PTGS1KIF11CES2P2RX1GABRA1 | |
| SCHEMBL29886876 | 0.79 | CES2 (0.56) | PTGS1KIF11CES2P2RX1GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655456-A | Method for efficiently purifying and separating 2-chloro-4-trifluoromethyl phenol | 上虞颖泰精细化工有限公司 | 2023-08-29 | — | — | CN | claimed |
| US-10029992-B2 | Diaminotriazine compounds and their use as herbicides | BASF SE (DE) | 2018-07-24 | — | — | US | claimed |
| EP-3134391-A1 | DIAMINOTRIAZINE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2017-03-01 | — | — | EP | claimed |
| US-20170044114-A1 | Diaminotriazine compounds and their use as herbicides | BASF SE (DE) | 2017-02-16 | — | — | US | claimed |
| WO-2015162166-A1 | DIAMINOTRIAZINE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2015-10-29 | — | — | WO | claimed |
| EP-4735433-A2 | SUBSTITUTED PYRIDAZINE COMPOUNDS AS INHIBITORS OF NLRP3 ACTIVITY AND THERAPEUTIC USES THEREOF | Viva Star Biosciences (US) Inc. (US) | 2026-05-06 | — | — | EP | disclosed |
| US-20250270188-A1 | NLRP3 INFLAMMASOME INHIBITORS | NOVARTIS AG (CH) | 2025-08-28 | — | — | US | disclosed |
| US-20250115558-A1 | PYRIDAZINE DERIVATIVES AND RELATED USES | NODTHERA LTD (GB) | 2025-04-10 | — | — | US | disclosed |
| WO-2025049746-A1 | COMPOSITIONS COMPRISING WERNER SYNDROME HELICASE INHIBITORS AND METHODS OF USING THE SAME | EIKON THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |
| WO-2025006681-A2 | SUBSTITUTED PYRIDAZINE COMPOUNDS AS INHIBITORS OF NLRP3 ACTIVITY AND THERAPEUTIC USES THEREOF | VIVA STAR BIOSCIENCES (US) INC. (US) | 2025-01-02 | — | — | WO | disclosed |
| US-12139471-B2 | NLRP3 inflammasome inhibitors | NOVARTIS AG (CH) | 2024-11-12 | — | — | US | disclosed |
| US-11827596-B2 | Thyromimetics | AUTOBAHN THERAPEUTICS, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| WO-2012162407-A1 | PICOLINAMIDO - PROPANOIC ACID DERIVATIVES USEFUL AS GLUCAGON RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2012-11-29 | — | — | WO | disclosed |
| US-20120302610-A1 | PICOLINAMIDO-PROPANOIC ACID DERIVATIVES USEFUL AS GLUCAGON RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2012-11-29 | — | — | US | disclosed |
| WO-2012076435-A1 | PYRIMIDINONE COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES OR CONDITIONS MEDIATED BY LP - PLA2 | GLAXO GROUP LIMITED (GB) | 2012-06-14 | — | — | WO | disclosed |
| US-20120142717-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-06-07 | — | — | US | disclosed |
| US-6828466-B2 | Reacting arene with borane; oxidation, hydrogenation phenylboronic acid | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2004-12-07 | — | — | US | disclosed |
| US-20040147788-A1 | Stilbene derivatives and their use as aryl hydrocarbon receptor antagonistic ligands | INSTITUTE NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (I.N.S.E.R.M.) (FR) | 2004-07-29 | — | — | US | disclosed |
| EP-1418164-A1 | New stilbene derivatives and their use as aryl hydrocarbon receptor ligand antagonists | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2004-05-12 | — | — | EP | disclosed |
| US-20040030197-A1 | Process for the synthesis of phenols from arenes | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2004-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147788-A1 | Stilbene derivatives and their use as aryl hydrocarbon receptor antagonistic ligands | AHR, HCAR3, HCAR1 | RAPGEF4 4136/4885HCAR1 3/4885AHR 1/4885 |
| US-20120142717-A1 | COMPOUNDS | LIPG, PLA2G1B, ENPP2 | RAPGEF4 439/4885HCAR1 736/4885AHR 4301/4885 |
| US-20250115558-A1 | PYRIDAZINE DERIVATIVES AND RELATED USES | IL1B, NLRP3, NOD1 | RAPGEF4 1701/4885HCAR1 191/4885AHR 537/4885 |
| US-10029992-B2 | Diaminotriazine compounds and their use as herbicides | NR4A3, CBR3, RCOR3 | RAPGEF4 2744/4885HCAR1 505/4885AHR 137/4885 |
| US-12139471-B2 | NLRP3 inflammasome inhibitors | NLRP3, NLRP1, NOD1 | RAPGEF4 1224/4885HCAR1 71/4885AHR 222/4885 |
| US-11827596-B2 | Thyromimetics | TPO, TSHR, TTR | RAPGEF4 2329/4885HCAR1 800/4885AHR 2604/4885 |
| US-20120302610-A1 | PICOLINAMIDO-PROPANOIC ACID DERIVATIVES USEFUL AS GLUCAGON RECEPTOR ANTAGONISTS | GLP1R, GIPR, GCGR | RAPGEF4 1254/4885HCAR1 61/4885AHR 1027/4885 |
| US-20250270188-A1 | NLRP3 INFLAMMASOME INHIBITORS | NLRP3, NLRP1, NOD1 | RAPGEF4 1224/4885HCAR1 71/4885AHR 222/4885 |
| US-20040030197-A1 | Process for the synthesis of phenols from arenes | GRHPR, CBR1, CBR3 | RAPGEF4 2158/4885HCAR1 12/4885AHR 14/4885 |
| US-20170044114-A1 | Diaminotriazine compounds and their use as herbicides | NR4A3, CBR3, RCOR3 | RAPGEF4 2790/4885HCAR1 514/4885AHR 139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.