Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3199580 | 0.85 | KMT2A (0.41) | KMT2AHTTNPSR1CHRNB2CHRNB4 | |
| SCHEMBL5049712 | 0.82 | KDM4E (0.38) | KMT2AMEN1PLA2G1BHTTNPSR1 | |
| SCHEMBL30489371 | 0.81 | KMT2A (0.55) | KMT2AMEN1PLA2G1BHTTNPSR1 | |
| SCHEMBL10527071 | 0.81 | KMT2A (0.50) | KMT2AMEN1PLA2G1BHTTNPSR1 | |
| SCHEMBL28995221 | 0.80 | KMT2A (0.53) | KMT2AMEN1PLA2G1BHTTNPSR1 | |
| SCHEMBL9191050 | 0.80 | KMT2A (0.48) | KMT2AMEN1PLA2G1BHTTNPSR1 | |
| Hydrochloric Acid SCHEMBL10590655 | 0.80 | KMT2A (0.53) | KMT2AMEN1PLA2G1BHTTNPSR1 | |
| SCHEMBL22321965 | 0.80 | KDM4E (0.36) | KMT2AMEN1PLA2G1BHTTNPSR1 | |
| SCHEMBL6553514 | 0.80 | LAP3 (0.36) | KMT2AMEN1PLA2G1BHTTNPSR1 | |
| SCHEMBL382026 | 0.80 | KDM4E (0.36) | KMT2AMEN1PLA2G1BHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1679302-B1 | AROMATIC AMINO ACID LABELED WITH STABLE ISOTOPE, METHOD FOR INCORPORATING THE SAME INTO TARGET PROTEIN AND METHOD FOR ANALYZING PROTEIN STRUCTURE USING NMR | JAPAN SCIENCE & TECH AGENCY (JP) | 2014-04-30 | — | — | EP | disclosed |
| US-8440169-B2 | Stable isotope-labeled aromatic amino acids, method for incorporating the same in target protein and method for NMR-structural analysis of proteins | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2013-05-14 | — | — | US | disclosed |
| US-20100056799-A1 | Stable Isotope-Labeled Aromatic Amino Acids, Method for Incorporating the Same in Target Protein and Method for NMR-Structural Analysis of Proteins | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-03-04 | — | — | US | disclosed |
| US-7608248-B2 | Stable isotope-labeled aromatic amino acids, method for incorporating the same in target protein and method for NMR-structural analysis of proteins | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2009-10-27 | — | — | US | disclosed |
| US-20060194328-A1 | Stable isotope-labeled aromatic amino acids, method for incorporating the same in target protein and method for NMR-structural analysis of proteins | JAPAN SCIENCE AND TECHNOLOGY AGENCY | 2006-08-31 | — | — | US | disclosed |
| EP-1679302-A1 | AROMATIC AMINO ACID LABELED WITH STABLE ISOTOPE, METHOD FOR INCORPORATING THE SAME INTO TARGET PROTEIN AND METHOD FOR ANALYZING PROTEIN STRUCTURE USING NMR | Japan Science and Technology Agency (JP) | 2006-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056799-A1 | Stable Isotope-Labeled Aromatic Amino Acids, Method for Incorporating the Same in Target Protein and Method for NMR-Structural Analysis of Proteins | BCAT1, DDC, PAH | KMT2A 2489/4885MEN1 4285/4885PLA2G1B 4496/4885 |
| US-20060194328-A1 | Stable isotope-labeled aromatic amino acids, method for incorporating the same in target protein and method for NMR-structural analysis of proteins | BCAT1, DDC, PAH | KMT2A 2489/4885MEN1 4285/4885PLA2G1B 4496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.