Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4483852 | 0.81 | TRPA1 (0.44) | MAPK1ALDH1A1HSD17B10TDP1ALOX15 | |
| SCHEMBL24806431 | 0.80 | CYP3A4 (0.52) | CYP3A4MAPK1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL30628003 | 0.77 | TRPA1 (0.46) | CYP3A4MAPK1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL20457057 | 0.77 | CYP3A4 (0.33) | CYP3A4ALDH1A1TSHRMAPT | |
| SCHEMBL394780 | 0.77 | TRPA1 (0.46) | CYP3A4MAPK1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL26501861 | 0.77 | CYP3A4 (0.38) | CYP3A4MAPK1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL24069516 | 0.77 | CYP3A4 (0.38) | CYP3A4MAPK1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL31192614 | 0.76 | ALDH1A1 (0.45) | CYP3A4MAPK1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL6230443 | 0.76 | CYP3A4 (0.41) | CYP3A4MAPK1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL105824 | 0.76 | ALDH1A1 (0.45) | CYP3A4MAPK1ALDH1A1HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230049231-A1 | ARYL HETEROBICYCLIC COMPOUNDS AS Kv1.3 POTASSIUM SHAKER CHANNEL BLOCKERS | D. E. SHAW RESEARCH, LLC | 2023-02-16 | — | — | US | disclosed |
| US-20230040182-A1 | ARYL HETEROBICYCLIC COMPOUNDS AS Kv1.3 POTASSIUM SHAKER CHANNEL BLOCKERS | D. E. SHAW RESEARCH, LLC | 2023-02-09 | — | — | US | disclosed |
| US-20230026611-A1 | ARYL HETEROCYCLIC COMPOUNDS AS Kv1.3 POTASSIUM SHAKER CHANNEL BLOCKERS | D. E. SHAW RESEARCH, LLC | 2023-01-26 | — | — | US | disclosed |
| EP-1967803-B1 | METHOD FOR DRYING A COATED FILM | FUJIFILM CORP (JP) | 2016-09-28 | — | — | EP | disclosed |
| US-8196312-B2 | Drying method and apparatus for drying object | FUJIFILM CORPORATION (JP) | 2012-06-12 | — | — | US | disclosed |
| CN-101360965-B | Method and apparatus for drying object to be dried | FUJI PHOTO FILM CO LTD | 2010-12-22 | — | — | CN | disclosed |
| US-20100058609-A1 | DRYING METHOD AND APPARATUS FOR DRYING OBJECT | FUJIFILM CORPORATION (JP) | 2010-03-11 | — | — | US | disclosed |
| CN-101360965-A | Method and apparatus for drying object to be dried | FUJIFILM CORP (JP) | 2009-02-04 | — | — | CN | disclosed |
| EP-1967803-A1 | METHOD AND APPARATUS FOR DRYING SUBSTANCE TO BE DRIED | FUJIFILM Corporation (JP) | 2008-09-10 | — | — | EP | disclosed |
| US-4123279-A | PHENOLIC RESINS, INK RECEPTIVITY | FUJI PHOTO FILM CO., LTD. (JP) | 1978-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230040182-A1 | ARYL HETEROBICYCLIC COMPOUNDS AS Kv1.3 POTASSIUM SHAKER CHANNEL BLOCKERS | KCNB1, KCNJ2, KCNB2 | CYP3A4 378/4885MAPK1 1010/4885ALDH1A1 3120/4885 |
| US-20230049231-A1 | ARYL HETEROBICYCLIC COMPOUNDS AS Kv1.3 POTASSIUM SHAKER CHANNEL BLOCKERS | KCNB1, KCNJ2, KCNB2 | CYP3A4 378/4885MAPK1 1010/4885ALDH1A1 3120/4885 |
| US-20230026611-A1 | ARYL HETEROCYCLIC COMPOUNDS AS Kv1.3 POTASSIUM SHAKER CHANNEL BLOCKERS | KCNA3, KCNH2, KCNJ2 | CYP3A4 373/4885MAPK1 530/4885ALDH1A1 1910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.