SCHEMBL394780

SCHEMBL394780

Cc1ccc(O)c(C(C)(C)C)c1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.46
ATM Q13315 1/20 0.46
ESR1 P03372 5/20 0.41
ALDH1A1 P00352 7/20 0.38
ALOX15 P16050 5/20 0.38
TDP1 Q9NUW8 4/20 0.38
HSD17B10 Q99714 3/20 0.38
HPGD P15428 2/20 0.38
LMNA P02545 2/20 0.37
CYP2C9 P11712 2/20 0.37
TYR P14679 2/20 0.37
NR1I2 O75469 1/20 0.37
MIF P14174 1/20 0.37
HTT P42858 1/20 0.37
NFE2L2 Q16236 1/20 0.37
TP53 P04637 2/20 0.36
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
ESR2 Q92731 4/20 0.35
TSHR P16473 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30628003 1.00 TRPA1 (0.46) TRPA1ATMESR1ALDH1A1ALOX15
SCHEMBL4872313 0.86 ESR1 (0.46) TRPA1ATMESR1ALDH1A1ALOX15
SCHEMBL4483852 0.85 TRPA1 (0.44) TRPA1ATMESR1ALDH1A1ALOX15
SCHEMBL29359879 0.83 ESR1 (0.43) TRPA1ATMESR1ALDH1A1ALOX15
SCHEMBL36472 0.83 ESR1 (0.43) TRPA1ATMESR1ALDH1A1ALOX15
SCHEMBL2051069 0.81 TRPA1 (0.46) TRPA1ATMESR1ALDH1A1ALOX15
SCHEMBL4503429 0.81 GABRA1 (0.45) TRPA1ATMESR1ALDH1A1ALOX15
SCHEMBL30438308 0.81 TRPA1 (0.46) TRPA1ATMESR1ALDH1A1ALOX15
SCHEMBL31612514 0.81 GABRA1 (0.45) TRPA1ATMESR1ALDH1A1ALOX15
SCHEMBL8890931 0.81 ESR1 (0.41) TRPA1ATMESR1ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 889 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024134058-A1 FUEL COMPOSITION COMPRISING A RENEWABLE BASE, A FATTY ACID ESTER AND AN ALKYL-PHENOL ADDITIVE TOTALENERGIES ONETECH (FR) 2024-06-27 WO claimed
EP-4065671-B1 USE OF ALKYL PHENOL COMPOUNDS AS DETERGENT ADDITIVES FOR PETROLS TOTALENERGIES ONETECH (FR) 2024-06-05 EP claimed
EP-4373903-A1 USE OF A COMPOSITION OF ADDITIVES FOR REDUCING DIESEL VEHICLE EMISSIONS TotalEnergies OneTech (FR) 2024-05-29 EP claimed
WO-2023002108-A1 USE OF A COMPOSITION OF ADDITIVES FOR REDUCING DIESEL VEHICLE EMISSIONS TOTALENERGIES ONETECH (FR) 2023-01-26 WO claimed
WO-2021105268-A1 USE OF ALKYL PHENOL COMPOUNDS AS DETERGENT ADDITIVES FOR PETROLS TOTAL MARKETING SERVICES (FR) 2021-06-03 WO claimed
EP-3221415-A1 NON-AZEOTROPIC FLUID MIXTURE FOR AIR CONDITIONING DEVICES PSK Research, LLC (US) 2017-09-27 EP claimed
US-9765250-B2 Non-azeotropic fluid mixure for air conditioning devices PSK Research, LLC (US) 2017-09-19 US claimed
CN-107075352-A Non-azeotropic fluid mixtures for air conditioning equipment PSK研究有限责任公司 2017-08-18 CN claimed
WO-2016079575-A1 NON-AZEOTROPIC FLUID MIXTURE FOR AIR CONDITIONING DEVICES PSK Research, LLC (US) 2016-05-26 WO claimed
US-20160137894-A1 NON-AZEOTROPIC FLUID MIXTURE FOR AIR CONDITIONING DEVICES PSK Research, LLC (US) 2016-05-19 US claimed
WO-2013103980-A2 ACRYLIC SPRAY ENAMELITE LLC (US) 2013-07-11 WO claimed
CN-101914173-A Controllable polymerization method of industrial-grade monomer UNIV SUZHOU 2010-12-15 CN claimed
US-20060218855-A1 Method of increasing the oxidation stability of biodiesel DEGUSSA AG (DE) 2006-10-05 US claimed
US-20260146193-A1 WORKING MEDIUM FOR HEAT CYCLE, METHOD FOR STORING WORKING MEDIUM FOR HEAT CYCLE, METHOD FOR MANUFACTURING WORKING MEDIUM FOR HEAT CYCLE,COMPOSITION FOR HEAT CYCLE SYSTEM, AND STORAGE CONTAINER FOR WORKING MEDIUM FOR HEAT CYCLE AGC Inc. (JP) 2026-05-28 US disclosed
CN-116659004-B Air conditioner DAIKIN INDUSTRIES, LTD. (JP) 2026-05-26 CN disclosed
CN-122080863-A Mixed refrigerant and preparation method and application thereof 2026-05-26 CN disclosed
US-4392000-A Stabilized compositions of chlorinated solvents SOLVAY & CIE. (BE) 1983-07-05 US disclosed
EP-0078998-A2 Liquid hydrocarbon fuel containing a polyisobutylene and its use in a gas turbine powered aircraft BASF Aktiengesellschaft (DE) 1983-05-18 EP disclosed
EP-0050890-A1 Stabilized compositions of chlorinated solvents SOLVAY & Cie (Société Anonyme) (BE) 1982-05-05 EP disclosed
US-4113635-A MONO-, DI-, OR TRI-PARTIAL ESTERS OF PENTAERYTHRITOL AND FATTY ACIDS NIPPON STEEL CORPORATION (JP) 1978-09-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146193-A1 WORKING MEDIUM FOR HEAT CYCLE, METHOD FOR STORING WORKING MEDIUM FOR HEAT CYCLE, METHOD FOR MANUFACTURING WORKING MEDIUM FOR HEAT CYCLE,COMPOSITION FOR HEAT CYCLE SYSTEM, AND STORAGE CONTAINER FOR WORKING MEDIUM FOR HEAT CYCLE TMEM14C, NEFM, RFC2 TRPA1 1605/4885ATM 1204/4885ESR1 3165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.