SCHEMBL4226829

SCHEMBL4226829

CCN(CC)c1ccc(C2(c3c(C)n(C)c4ccccc34)OC(=O)c3ccccc32)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.40
NPSR1 Q6W5P4 4/20 0.40
CFTR P13569 1/20 0.40
GOPC Q9HD26 1/20 0.40
MAPT P10636 6/20 0.40
MEN1 O00255 5/20 0.40
KMT2A Q03164 5/20 0.40
ALDH1A1 P00352 5/20 0.40
CYP3A4 P08684 4/20 0.40
TDP1 Q9NUW8 3/20 0.40
POLB P06746 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
HSD17B10 Q99714 3/20 0.40
GPR55 Q9Y2T6 2/20 0.40
TSHR P16473 2/20 0.40
ESR1 P03372 1/20 0.40
TP53 P04637 1/20 0.40
TYMS P04818 1/20 0.40
ALOX15 P16050 1/20 0.40
ESR2 Q92731 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10933798 0.90 LMNA (0.38) LMNANPSR1CFTRGOPCMAPT
SCHEMBL29363012 0.89 LMNA (0.40) LMNANPSR1CFTRGOPCMAPT
SCHEMBL27274 0.89 LMNA (0.40) LMNANPSR1CFTRGOPCMAPT
SCHEMBL29385861 0.89 TDP1 (0.50) LMNANPSR1CFTRGOPCMAPT
SCHEMBL395450 0.89 TDP1 (0.50) LMNANPSR1CFTRGOPCMAPT
SCHEMBL25194167 0.88 PGR (0.38) LMNANPSR1CFTRGOPCMAPT
SCHEMBL29460366 0.87 MAPT (0.44) LMNANPSR1CFTRGOPCMAPT
SCHEMBL1370527 0.87 MAPT (0.44) LMNANPSR1CFTRGOPCMAPT
Oxirane SCHEMBL10438874 0.85 ALDH1A1 (0.39) LMNANPSR1CFTRGOPCMAPT
SCHEMBL3219191 0.83 LMNA (0.49) LMNANPSR1CFTRGOPCMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210039414-A1 IMAGING MEDIUM HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2021-02-11 US disclosed
EP-1440888-B1 Method for issuing a label with thermosensitive adhesive RICOH KK (JP) 2009-12-16 EP disclosed
US-7021214-B2 Method for issuing label with thermosensitive adhesive RICOH COMPANY, LTD. (JP) 2006-04-04 US disclosed
US-20040163556-A1 Method for issuing label with thermosensitive adhesive RICOH COMPANY, LTD. 2004-08-26 US disclosed
EP-1440888-A1 Method for issuing a label with thermosensitive adhesive Ricoh Company (JP) 2004-07-28 EP disclosed