SCHEMBL3219729

SCHEMBL3219729

Fc1cc(F)c(F)c(F)n1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA13 Q8N1Q1 1/20 0.33
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29580297 1.00 CA12 (0.33) CA12CA1CA2CA7CA13
SCHEMBL15624384 0.77 ALDH1A1 (0.31) ALDH1A1LMNACES2CES1
SCHEMBL4850782 0.72 MEN1 (0.31)
SCHEMBL11942296 0.72 POLB (0.35) CA12CA1CA2CA7CA13
SCHEMBL18700724 0.72 HDAC1 (0.31)
SCHEMBL24103030 0.72
SCHEMBL30930521 0.72 ALDH1A1 (0.38) CA12CA1CA2CA7CA13
SCHEMBL1099814 0.72
SCHEMBL1099817 0.72 KMT2A (0.30)
SCHEMBL16908181 0.72 ALDH1A1 (0.38) CA12CA1CA2CA7CA13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3149020-A2 CHEMICALLY MODIFYING PEPTIDES The University of Durham (GB) 2017-04-05 EP claimed
EP-3149021-A1 CYCLISING PEPTIDES The University of Durham (GB) 2017-04-05 EP claimed
WO-2015181545-A1 CYCLISING PEPTIDES THE UNIVERSITY OF DURHAM (GB) 2015-12-03 WO claimed
WO-2015181544-A2 CHEMICALLY MODIFYING PEPTIDES THE UNIVERSITY OF DURHAM (GB) 2015-12-03 WO claimed
EP-4363409-B1 METHOD FOR THE PRODUCTION OF ALKYLENE OXIDES COVESTRO DEUTSCHLAND AG (DE) 2025-06-11 EP disclosed
EP-4363409-A1 METHOD FOR PRODUCING ALKYLENE OXIDES Covestro Deutschland AG (DE) 2024-05-08 EP disclosed
CN-117448850-A Universal method for preparing polyfluoro biaryl compound without transition metal 中国科学院理化技术研究所 2024-01-26 CN disclosed
WO-2023274993-A1 METHOD FOR PRODUCING ALKYLENE OXIDES COVESTRO DEUTSCHLAND AG (DE) 2023-01-05 WO disclosed
EP-4112609-A1 METHOD FOR THE PRODUCTION OF ALKYLENE OXIDES Covestro Deutschland AG (DE) 2023-01-04 EP disclosed
CN-110491999-B Modification method of electron transport layer for organic solar cell 太原理工大学 2022-04-12 CN disclosed
US-10906932-B2 Cyclising peptides THE UNIVERSITY OF DURHAM (GB) 2021-02-02 US disclosed
US-10906932-B2 Cyclising peptides THE UNIVERSITY OF DURHAM (GB) 2021-02-02 US disclosed
WO-2015181545-A1 CYCLISING PEPTIDES THE UNIVERSITY OF DURHAM (GB) 2015-12-03 WO disclosed
WO-2015181544-A2 CHEMICALLY MODIFYING PEPTIDES THE UNIVERSITY OF DURHAM (GB) 2015-12-03 WO disclosed
WO-2010026075-A1 PYRIDINE DERIVATIVES AS INHIBITORS OF HIV-I REVERSE TRANSCRIPTASE F. HOFFMANN-LA ROCHE AG (CH) 2010-03-11 WO disclosed
WO-2010026075-A1 PYRIDINE DERIVATIVES AS INHIBITORS OF HIV-I REVERSE TRANSCRIPTASE F. HOFFMANN-LA ROCHE AG (CH) 2010-03-11 WO disclosed
US-20100056535-A1 Inhibitors of HIV-1 reverse transcriptase ROCHE PALO ALTO LLC 2010-03-04 US disclosed
US-20100056535-A1 Inhibitors of HIV-1 reverse transcriptase ROCHE PALO ALTO LLC 2010-03-04 US disclosed
US-20100056535-A1 Inhibitors of HIV-1 reverse transcriptase ROCHE PALO ALTO LLC 2010-03-04 US disclosed
WO-1997049697-A1 PYRIDYLAMINOPYRIMIDINES AS FUNGICIDES ZENECA LIMITED (GB) 1997-12-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100056535-A1 Inhibitors of HIV-1 reverse transcriptase QTRT1, NQO2, QTRT2 CA12 4842/4885CA1 4639/4885CA2 4603/4885
US-10906932-B2 Cyclising peptides VIP, NGLY1, NPPA CA12 692/4885CA1 654/4885CA2 3784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.