Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 5/20 | 0.34 |
| ▸ | HRH1 | P35367 | 4/20 | 0.34 |
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | PRCP | P42785 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3221191 | 0.76 | — | — | |
| SCHEMBL3214158 | 0.76 | HTR2A (0.33) | SIGMAR1HTR2A | |
| SCHEMBL4906291 | 0.75 | SIGMAR1 (0.35) | SIGMAR1HTR2APRCP | |
| SCHEMBL29501701 | 0.71 | SIGMAR1 (0.43) | SIGMAR1HTR2A | |
| SCHEMBL8061057 | 0.70 | HTR2A (0.39) | SIGMAR1HTR2AADRA1DADRA1AADRA1B | |
| SCHEMBL9281778 | 0.69 | SIGMAR1 (0.51) | SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL3965241 | 0.69 | ADRA1D (0.39) | SIGMAR1ADRA1DADRA1AADRA1BPRCP | |
| SCHEMBL3231447 | 0.68 | SIGMAR1 (0.34) | SIGMAR1HTR2AADRA1DADRA1AADRA1B | |
| SCHEMBL15908323 | 0.68 | HTR2A (0.43) | SIGMAR1HTR2AHRH1HTR2CHTR2B | |
| SCHEMBL3231725 | 0.68 | SIGMAR1 (0.32) | SIGMAR1ADRA1DADRA1AADRA1BPRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2009304-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-10-01 | — | — | EP | disclosed |
| EP-2003353-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-06-04 | — | — | EP | disclosed |
| US-8230986-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-31 | — | — | US | disclosed |
| US-8220609-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20100184519-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |
| US-20090173591-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-2009304-A1 | TORQUE LIMITER | JTEKT Corporation (JP) | 2008-12-31 | — | — | EP | disclosed |
| EP-2003353-A1 | TORQUE LIMITER | JTEKT Corporation (JP) | 2008-12-17 | — | — | EP | disclosed |