Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | FBP1 | P09467 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 6/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3219977 | 1.00 | MEN1 (0.63) | MEN1KMT2AFBP1ALDH1A1KDM4E | |
| SCHEMBL28313969 | 0.81 | FBP1 (0.56) | MEN1KMT2AFBP1ALDH1A1KDM4E | |
| SCHEMBL3232417 | 0.81 | FBP1 (0.56) | MEN1KMT2AFBP1ALDH1A1KDM4E | |
| SCHEMBL3232414 | 0.81 | FBP1 (0.56) | MEN1KMT2AFBP1ALDH1A1KDM4E | |
| SCHEMBL9850705 | 0.80 | FBP1 (0.59) | MEN1KMT2AFBP1ALDH1A1KDM4E | |
| Maleic Acid SCHEMBL25346301 | 0.79 | MEN1 (0.54) | MEN1KMT2AFBP1ALDH1A1KDM4E | |
| SCHEMBL481147 | 0.79 | AKR1C3 (0.58) | MEN1KMT2AFBP1ALDH1A1KDM4E | |
| SCHEMBL52681 | 0.79 | AKR1C3 (0.58) | MEN1KMT2AFBP1ALDH1A1KDM4E | |
| SCHEMBL17009045 | 0.79 | AKR1C3 (0.58) | MEN1KMT2AFBP1ALDH1A1KDM4E | |
| SCHEMBL11980044 | 0.79 | KMT2A (0.48) | MEN1KMT2AFBP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236985-B2 | Compounds and uses thereof | IMPERIAL INNOVATIONS LTD. (GB) | 2012-08-07 | — | — | US | disclosed |
| US-20100063144-A1 | COMPOUNDS AND USES THEREOF | IMPERIAL INNOVATIONS LTD (GB) | 2010-03-11 | — | — | US | disclosed |
| WO-2008050125-A1 | COMPOUNDS AND USES THEREOF | IMPERIAL INNOVATIONS LTD. (GB) | 2008-05-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063144-A1 | COMPOUNDS AND USES THEREOF | HDAC1, HDAC11, HDAC2 | MEN1 1240/4885KMT2A 58/4885FBP1 300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.