Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3232414 | 1.00 | FBP1 (0.56) | FBP1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL6243038 | 0.91 | MEN1 (0.55) | FBP1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL6243035 | 0.91 | MEN1 (0.55) | FBP1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL6954094 | 0.82 | FBP1 (0.61) | FBP1MEN1KMT2AALDH1A1APP | |
| SCHEMBL9850705 | 0.81 | FBP1 (0.59) | FBP1MEN1KMT2AALDH1A1APP | |
| SCHEMBL3219977 | 0.81 | MEN1 (0.63) | FBP1MEN1KMT2AALDH1A1APP | |
| SCHEMBL3219973 | 0.81 | MEN1 (0.63) | FBP1MEN1KMT2AALDH1A1APP | |
| SCHEMBL10507269 | 0.80 | GLO1 (0.68) | FBP1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL10511400 | 0.80 | GLO1 (0.68) | FBP1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL6469686 | 0.79 | FBP1 (0.67) | FBP1MEN1KMT2AALDH1A1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56034654-A | — | — | None | — | — | JP | disclosed |
| CN-107089980-B | A kind of chirality benzo [a] quinolizine -2- ketone compounds and its asymmetry catalysis synthetic method | 合肥工业大学 | 2019-08-30 | — | — | CN | disclosed |
| EP-2958909-A1 | BICYCLO 2,3-BENZODIAZEPINES AND SPIROCYCLICALLY SUBSTITUTED 2,3-BENZODIAZEPINES | Bayer Pharma Aktiengesellschaft (DE) | 2015-12-30 | — | — | EP | disclosed |
| WO-2014128067-A1 | BICYCLO 2,3-BENZODIAZEPINES AND SPIROCYCLICALLY SUBSTITUTED 2,3-BENZODIAZEPINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-08-28 | — | — | WO | disclosed |
| US-8236985-B2 | Compounds and uses thereof | IMPERIAL INNOVATIONS LTD. (GB) | 2012-08-07 | — | — | US | disclosed |
| US-20100063144-A1 | COMPOUNDS AND USES THEREOF | IMPERIAL INNOVATIONS LTD (GB) | 2010-03-11 | — | — | US | disclosed |
| WO-2005011661-A1 | PHARMACEUTICAL AGENTS | UNIVERSITY COLLEGE LONDON (GB) | 2005-02-10 | — | — | WO | disclosed |
| US-4566900-A | PRE- AND POSTEMERGENCE HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1986-01-28 | — | — | US | disclosed |
| JP-S5634654-A | PREPARATION OF C2N+3 CYCLOALK A -N-EN-1-ONE | OGAWA HARU | 1981-04-06 | — | — | JP | disclosed |
| US-4087549-A | Sulphonic acid containing indenyl derivatives | MERCK & CO., INC. (US) | 1978-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063144-A1 | COMPOUNDS AND USES THEREOF | HDAC1, HDAC11, HDAC2 | FBP1 300/4885MEN1 1240/4885KMT2A 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.