Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 10/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL321765 | 0.87 | RORC (0.43) | RORCALDH1A1KDM4EGAAHPGD | |
| SCHEMBL321532 | 0.83 | NPC1 (0.44) | MAPK8RORCALDH1A1KDM4EGAA | |
| SCHEMBL322579 | 0.81 | NPC1 (0.41) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL322450 | 0.79 | MAPT (0.39) | RORCALDH1A1KDM4EGAAHPGD | |
| SCHEMBL17074451 | 0.78 | KDM4E (0.39) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL322513 | 0.78 | RORC (0.44) | RORCALDH1A1KDM4EGAAHPGD | |
| SCHEMBL323215 | 0.78 | HTR3A (0.39) | RORCALDH1A1KDM4EGAAHPGD | |
| SCHEMBL322566 | 0.77 | RORC (0.43) | MAPK8RORCCFTRALDH1A1KDM4E | |
| SCHEMBL14916347 | 0.76 | PARP1 (0.36) | RORCALDH1A1KDM4EGAAHPGD | |
| SCHEMBL323368 | 0.76 | NPC1 (0.43) | ALDH1A1KDM4EGAAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590976-A1 | IMIDAZOPYRIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004732-A1 | IMIDAZOPYRIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-01-12 | — | — | WO | disclosed |