Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.39 |
| ▸ | GAA | P10253 | 11/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.39 |
| ▸ | HPGD | P15428 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.39 |
| ▸ | GLA | P06280 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL327753 | 0.89 | KDM4E (0.41) | KDM4EGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL323012 | 0.82 | KDM4E (0.42) | KDM4EGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL323013 | 0.82 | KDM4E (0.37) | KDM4EGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL322528 | 0.82 | DAPK3 (0.42) | KDM4EGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL322028 | 0.78 | MAPK8 (0.34) | KDM4EGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL14927289 | 0.78 | ADORA3 (0.43) | KDM4EALDH1A1HPGDHSD17B10GLA | |
| SCHEMBL321649 | 0.77 | KDM4E (0.48) | KDM4EGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL323368 | 0.76 | NPC1 (0.43) | KDM4EGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL17074452 | 0.75 | KDM4E (0.39) | KDM4EGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL14917192 | 0.73 | ALDH1A1 (0.41) | KDM4EGAAALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590976-B1 | IMIDAZOPYRIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2015-09-16 | — | — | EP | disclosed |